Category:FL

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{{Huge|{{Bilingual|フラボノイドのデータベース|Flavonoid Database}}}}
 
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[[Image:FL.gif|thumb|150px|right|Figure 1: The Backbone of Flavonoid Structure]]
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The word "flavonoid" comes from its Latin origin ''flavus'' (yellow) with ''oid'', meaning yellow-ish.  It comes from its history as yellow natural dye (quercetin and kaempferol are the most widespread flavone dyes. See [[:Category:FL3F|flavone]]).
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The word "flavonoid" comes from its Latin origin ''flavus'' (yellow), meaning yellow-ish.  It comes from its history as yellow natural dye (quercetin and kaempferol are the most widespread flavone dyes. See [[:Category:FL3F|flavone]]).
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Chemically speaking, it is a class of plant secondary metabolites that have two benzene rings (each called A-ring and B-ring) connected by a chain of three carbons (Figure 1).
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The carbon chain, corresponding to the numbers 2,3,4 in Figure 1, is linked to a hydroxyl group in the A-ring to form the C-ring.  The class of flavonoids are usually determined by the modification pattern of the C-ring (Table 1).
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Flavonoid is utilized in many industrial processes from pigments to food additives.  Often heard names include anthocyanin, catechin, flavan, and isoflavone.  
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フラボノイドの語源は,ラテン語の flavus （黄色）に「～のような」という意味の oid をつけたものです。これは代表的なフラボンであるquercetinやkaempferolが広く使われてきた黄色の天然色素であることに由来しています ([[:Category:FL3F|flavone]]参照)。
 
フラボノイドの語源は,ラテン語の flavus （黄色）に「～のような」という意味の oid をつけたものです。これは代表的なフラボンであるquercetinやkaempferolが広く使われてきた黄色の天然色素であることに由来しています ([[:Category:FL3F|flavone]]参照)。
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In chemistry terms, it is a class of plant secondary metabolites that have two benzene rings (each called A-ring and B-ring) connected by a chain of three carbons (Figure 1).
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The carbon chain, corresponding to the numbers 2,3,4 in Figure 1, is linked to a hydroxyl group in the A-ring to form the C-ring.  The class of flavonoids are usually determined by the modification pattern of the C-ring (Table 1).
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化学的な定義でフラボノイドとは, ベンゼン環2個 (それぞれA環B環と呼ばれる) を3つの炭素 (C) で結合した, 植物の代謝産物の総称です (Figure 1)。
 
化学的な定義でフラボノイドとは, ベンゼン環2個 (それぞれA環B環と呼ばれる) を3つの炭素 (C) で結合した, 植物の代謝産物の総称です (Figure 1)。
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Figure 1 において 2,3,4 と番号付けされた炭素鎖は A 環の水酸基と結合して C 環を構成します。フラボノイドのカテゴリーは,たいてい C 環の修飾パターンで決まります (Table 1)。
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Figure 1 において 2,3,4 と番号付けされた炭素鎖は A 環の水酸基と結合して C 環を構成します。フラボノイドのカテゴリーは,たいてい C 環の修飾パターンで決まります (Table 1)。}}
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[[Image:FL.gif|thumb|150px|right|Figure 1: The Backbone of Flavonoid Structure]]
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Flavonoid is utilized in many industrial processes from pigments to food additives.  Well known names include anthocyanin, catechin, flavan, and isoflavone.
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フラボノイドの用途は 色素から食品添加物まで多様です。 よく耳にするものでは, アントシアニン, カテキン, フラバン（茶）, イソフラボンなど, 全てフラボノイドです。
 
フラボノイドの用途は 色素から食品添加物まで多様です。 よく耳にするものでは, アントシアニン, カテキン, フラバン（茶）, イソフラボンなど, 全てフラボノイドです。
 
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<!--- Class Information (Do not delete. It is used by Template:Hierarchy.)
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<!--- Class Information (Do not delete. This list is used by Template:Hierarchy.)
 
&&FL&&Flavonoid&&
 
&&FL&&Flavonoid&&
 
&&FL1&&Aurone and Chalcone&&
 
&&FL1&&Aurone and Chalcone&&
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{{Category:FL/Biosynthesis}}
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==[[:Category:FL/Biosynthesis|{{Bilingual|生合成のページヘ|Biosynthesis}}]]==
  
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=={{Bilingual|生物活性|Bioactivity}}==
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==[[:Category:FL/Bioactivity|{{Bilingual|生物活性のページヘ|Bioactivity}}]]==
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==={{Bilingual|お茶|Tea Related}}===
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* [[Doc:Tea|Tea category]] 茶の種類
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* [[Doc:Tea/Consumption|Tea consumption]] 茶の消費量
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* [[Doc:Tea/Health|Tea and health]]　茶と健康
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==={{Bilingual|その他|Others}}===
 
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;{{Bilingual|抗紫外、抗酸化作用|Photoprotectant, anti-oxidant activity}} [[Doc:Antioxidant| ({{Bilingual|''詳細''|''More Information''}}]])
 
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Not only anthocyanins but even simple structures such as chalcone can absorb UV wavelengths strongly. The ability of photoprotection is derived from its anti-oxidative activity.
 
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アントシアニンだけでなく、カルコンのような構造の簡単なフラボノイドでも紫外線をよく吸収します。効紫外線効果は効酸化作用に関係しています。
 
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;{{Bilingual|血圧効果作用|Hypotensive activity}}
 
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Quercetin in onions and flavanols in cocoa are said to reduce blood pressure in hypertensive animals <ref>Hooper L, Kroon PA, Rimm EB, et al. (2008) "Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials" Am J Clin Nutr 88:38–50 PMID 18614722</ref>, but their effect or mechanism is not clinically conclusive.
 
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玉葱のクエルセチンやココアのフラバノールは血圧降下作用があるといわれますが、その効果や医学的メカニズムははっきりしていません。
 
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;{{Bilingual|抗菌、抗カビ作用|Anti-bacteria, anti-fungal activity}}
 
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Tannins (proanthocyanidins) show anti-bacterial activity.
 
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タンニン (プロアントシアニジニン) は一般に抗菌、抗カビ作用があります。
 
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=={{Bilingual|代表例|Representative Names}}==
 
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<div style="column-count:2; -moz-column-count:2;">
 
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* [[:Category:FLI|isoflavonoid]] in beans (豆のイソフラボン)
 
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* [[:Category:FL7|anthocyanin]] in berries (ベリーのアントシアニン)
 
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* [[FL63ACNS0001|catechin]] in tea (お茶のカテキン)
 
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* [[FL5FACGL0013|rutin]] in buckwheat (ソバのルチン)
 
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* [[FL2FAEGS0001|hesperidin]] in orange (ミカンのヘスペリジン)
 
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* [[FL1CAANS0001|naringenin chalcone]] in tomato (トマトのナリンゲニンカルコン)
 
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=={{Bilingual|データベース統計|Database statistics/ranking}}==
 
=={{Bilingual|データベース統計|Database statistics/ranking}}==

Latest revision as of 11:10, 19 January 2017

Flavonoid Database

Contents

Flavonoid Top Molecule Index Author Index Journals Structure Search Food New Input

[edit] Class Overview

The word "flavonoid" comes from its Latin origin flavus (yellow), meaning yellow-ish. It comes from its history as yellow natural dye (quercetin and kaempferol are the most widespread flavone dyes. See flavone).

In chemistry terms, it is a class of plant secondary metabolites that have two benzene rings (each called A-ring and B-ring) connected by a chain of three carbons (Figure 1). The carbon chain, corresponding to the numbers 2,3,4 in Figure 1, is linked to a hydroxyl group in the A-ring to form the C-ring. The class of flavonoids are usually determined by the modification pattern of the C-ring (Table 1).

Figure 1: The Backbone of Flavonoid Structure

Flavonoid is utilized in many industrial processes from pigments to food additives. Well known names include anthocyanin, catechin, flavan, and isoflavone.

Table 1. Flavonoid Classification
1st Class
FL1: Anthochlor
(Aurone and Chalcone)

Fl1.png
safflower yellow

FL2: Flavanone

Fl2.png
white skin of orange

FL3: Flavone

Fl3.png
herbs like parsley, yellow dye

FL4: Dihydroflavonol

Fl4.png
antioxidant in grapes

FL5: Flavonol

Fl5.png
vegetables such as onion

FL6: Flavan
(Leucoanthocyanidin)

Fl6.png
tea, cocoa

FL7: Anthocyani(di)n

Fl7.png
purple vegetables/fruits

FLI: Isoflavonoid

Fli.png
beans

FLN: Neoflavonoid

Fln.png

[edit] Biosynthesis

[edit] Bioactivity

[edit] Database statistics/ranking

This database collects original references that report identification of flavonoid in various plant species. The database consists of three major namespaces: (flavonoid) compounds, plant species, and references. Currently, 6961 flavonoid structures, 3961 plant species, and 5215 references describing total 19861 metabolite-species relationships are registered.

class FL1
(chalcones) 		FL2
(flavanones) 		FL3
(flavones) 		FL4
(dihydroflavonols) 		FL5
(flavonols) 		FL6
(flavans) 		FL7
(anthocyanidins) 		FLI
(isoflavonoids) 		FLN
(neoflavonoids) 		Total
#data 690 705 1479 272 1943 291 574 916 96 6961


[edit] Flavonoid content in food

For details, please visit this page.

Food containing high Flavanone

Flavanones are rich in citrus, not in vegetables.

Food Flavanone
(mg/100g) 		食品名
grapefruit, raw or juice 14-53 グレープフルーツ　（生、ジュース）
orange and tangerine, raw or juice 13-33 オレンジ、みかん　(生、ジュース）
Food containing high flavone

Many herbs contain flavones. Parsley is rich in apigenin; celery and thyme in luteolin.

Food Flavone
(mg/100g) 		食品名
celery hearts, raw 19 セロリの芯 （生）
parsley, raw 302 パセリ　（生）
Food containing high flavonol

Flavonols are prevalent in vegetables, usually in small amounts. Onions, kales, hot peppers are good sources.

Food Flavonol
(mg/100g) 		食品名
buckwheat 23 そば
cranberry, juice 16 クランベリー　（ジュース）
onion, raw or boiled 5-20 たまねぎ　（生、ゆで等）
kale, raw or canned 18-34 ケール　(生、かんづめ）
Food containing high flavan

Catechins and epicatechins are contained in legumes and teas, but not in other vegetables.

Food Flavan
(mg/100g or 100ml) 		食品名
broadbeans, raw ～50 そらまめ　（生）
dark chocolate bar ～50 ダークチョコレート
black grapes 18 黒いブドウ
brewed black tea > 16 淹れた紅茶
brewed oolong tea 50 淹れたウーロン茶
brewed green tea > 50 淹れた緑茶
Food containing high anthocyanin

Anthocyanins are contained in berries. Vegetables supply only small amounts.

Food Anthocyanin
(mg/100g) 		食品名
blueberries, raw 113 ブルーベリー　（生）
sweet cherries, raw 116 さくらんぼ　（生）
elderberries, raw 749 エルダーベリー　（生）
raspberries, raw 49 ラズベリー　（生）
Vegetables and herbs with scarce flavonoids

The following vegetables and herbs have flavonoid contents less than 5 mg/100 g: beets, kidney beans, snap beans, cabbage, carrot, cauliflower, cucumber, endive, gourd, leek, lettuce, green peas, sweet pepper, potato, radish, tomato, oregano, perrilla, rosemary


[edit] Design of Flavonoid ID numbers

12-DIGIT

F L x x y y z z w c c c
x ... backbone structure (母核構造) 

FL1 aurone and chalcone; FL2 flavanone; FL3 flavone; FL4 Dihydroflavonol; FL5 Flavonol; FL6 Flavan; FL7 Anthocyanin; FLI Isoflavonoid; FLN Neoflavonoid

y ... hydroxylation pattern in A and B ring (水酸基パターン) 

Click above categories to see details. General description is here.

z ... glycosylation pattern (糖修飾パターン) 

Click above categories to see details. General description is here.

w ... halogenation etc. (ハロゲン等) 

Currently unused.

c ... serial number (通し番号)


[edit] For Users of Flavonoid Viewer

The flavonoid IDs used in this site is the same as those in Flavonoid Viewer in metabolome.jp except for the following FL7 category.

Anthocyanin glycosylated with other than glucose and galactose
Flavonoid Viewer
FL7A..GS 		→ This site
FL7A..GO

Subcategories

This category has the following 10 subcategories, out of 10 total.

F

  • FL1‎ (4 C)
  • FL2‎ (1 C)
  • FL3‎ (1 C)
  • FL4‎ (1 C)

F cont.

  • FL5‎ (1 C)
  • FL6‎ (4 C)
  • FL7‎ (2 C)
  • FLI‎ (10 C)

F cont.

  • FLN‎ (6 C)
  • [×] FLT‎ (empty)

Pages in category "FL"

The following 2 pages are in this category, out of 2 total.

F

Retrieved from "http://metabolomics.jp/mediawiki/index.php?title=Category:FL&oldid=315233"
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