PKS:Bact06

Polyketide Top

Species List

UniRef90 Class

UniRef50 Class

Gene Class

Domains (by CDD)

Domains (by MAPSI)

Streptomyces carzinostaticus subsp. neocarzinostaticus (GenBank AAM77986) all species
Class	iPKS-6-MSAS (length: 1753) all classes   Class 03b_bMSAS in KS domain phylogeny	Reliability	putative
Product	bicyclic 2-hydroxyl-5-methyl-naphthoic acid (NPA)(neocarzinostatin)	GeneName	ncsB
UniProt,UniRef90	[1] , [2]	UniRef50	[3]
Domain by MAPSI	KS-AT-DH-KR-ACP (notation help / all patterns)
Domain by CDD	KS-AT-DH-KR-PP (notation help / all patterns)
Domain by ITER-DB	{{{ITERDB}}} (notation help / all patterns)
Estimated Domain
Description	iterative type I polyketide synthase [Streptomyces carzinostaticus subsp. neocarzinostaticus]
Information	"ncsB, Iterative type I, catalyzes the biosynthesis of bicyclic 2-hydroxyl-5-methyl-naphthoic acid (NPA) for neocarzinostatin (NCS)"
References	Schmitt I, Lumbsch HT: Ancient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungi. PLoS One 4:e4437, 2009
Link	AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)