PKS:Aspe07
From Metabolomics.JP
Polyketide Top | Species List | UniRef90 Class | UniRef50 Class | Gene Class | Domains (by CDD) |
Domains (by MAPSI) |
Aspergillus westerdijkiae (GenBank [1]) all species | |||
---|---|---|---|
Class | (length: 5298) all classes Class in KS domain phylogeny | Reliability | |
Product | GeneName | aomsas | |
UniProt,UniRef90 | [2] , [3] | UniRef50 | [4] |
Domain by MAPSI | (notation help / all patterns) | ||
Domain by CDD | (notation help / all patterns) | ||
Domain by ITER-DB | {{{ITERDB}}} | ||
Estimated Domain | |||
Description | |||
Information | The predicted amino acid sequence of aomsas shows an identity of 40–56% with different methylsalicylic acid synthase genes found in Byssochlamys nivea, P. patulum, A. terreus and Streptomyces viridochromogenes. An aomsas knockout mutant “aoΔmsas” of A. westerdijkiae, not only lost the capacity to produce isoasperlactone and asperlactone, but also 6-methylsalicylic acid. The genetically complemented mutant ao+msas restored the biosynthesis of all the missing metabolites. | ||
References |
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Link | AspGD |
This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)