Enzyme:6.2.1.9

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC6.-.-.- Ligases. : EC6.2.-.- Forming carbon-sulfur bonds. : EC6.2.1.- Acid--thiol ligases.

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.2.1.9

malate:CoA ligase (ADP-forming)
Systematic Name	malate:CoA ligase (ADP-forming)
Common Name	malate-CoA ligase malyl-CoA synthetase malyl coenzyme A synthetase malate thiokinase

CoA + ATP + (S)-Malic acid = L-Malyl-CoA + ADP + Orthophosphate (links: = )

CoA <Mapping> AtomMap:BMCCPUAPf023$BMFYS4CAa020$0 (2S) -4- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3- dimethylbutanoyl] amino] propanoylamino] ethylsulfanyl] -2-hydroxy-4-oxobutanoic acid 1 ↔ 9 2 ↔ 10 3 ↔ 11 4 ↔ 12 5 ↔ 13 6 ↔ 14 7 ↔ 15 8 ↔ 16 9 ↔ 17 10 ↔ 18 11 ↔ 19 12 ↔ 20 13 ↔ 21 14 ↔ 22 15 ↔ 23 32 ↔ 40 33 ↔ 41 34 ↔ 43 35 ↔ 42 36 ↔ 44 37 ↔ 45 38 ↔ 46 39 ↔ 47 40 ↔ 48 41 ↔ 49 42 ↔ 50 43 ↔ 51 44 ↔ 52 45 ↔ 53 ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0020$0 ADP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 (S) -Malic acid <Mapping> AtomMap:BMFYS4DAq003$BMFYS4CAa020$0 (2S) -4- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3- dimethylbutanoyl] amino] propanoylamino] ethylsulfanyl] -2-hydroxy-4-oxobutanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4