Enzyme:1.1.1.34

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.1.-.- Acting on the CH-OH group of donors. : EC1.1.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.1.1.34

(R)-mevalonate:NADP+ oxidoreductase (CoA-acylating)
Systematic Name	(R)-mevalonate:NADP+ oxidoreductase (CoA-acylating)
Common Name	hydroxymethylglutaryl-CoA reductase (NADPH) hydroxymethylglutaryl coenzyme A reductase (reduced nicotinamideadenine dinucleotide phosphate) 3-hydroxy-3-methylglutaryl-CoA reductase beta-hydroxy-beta-methylglutaryl coenzyme A reductase HMGCoA reductase-mevalonate:NADP-oxidoreductase (acetylating-CoA)

2 NADP+ + CoA + (R)-Mevalonic acid = 2 NADPH + (S)-3-Hydroxy-3-methyl-glutaryl-CoA (links: NADP+ + CoA +  (R) -Mevalonic acid = NADPH +  (S) -3-Hydroxy-3-methyl-glutaryl-CoA)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 CoA <Mapping> AtomMap:BMCCPUAPf023$BMFYB5CAa008$0 (S) -3-Hydroxy-3-methyl-glutaryl-CoA 1 ↔ 11 2 ↔ 12 3 ↔ 13 4 ↔ 14 5 ↔ 15 6 ↔ 16 7 ↔ 17 8 ↔ 18 9 ↔ 19 10 ↔ 20 11 ↔ 21 12 ↔ 22 13 ↔ 23 14 ↔ 24 15 ↔ 25 32 ↔ 42 33 ↔ 43 34 ↔ 45 35 ↔ 44 36 ↔ 46 37 ↔ 47 38 ↔ 48 39 ↔ 49 40 ↔ 50 41 ↔ 51 42 ↔ 52 43 ↔ 53 44 ↔ 54 45 ↔ 55 (R) -Mevalonic acid <Mapping> AtomMap:BMFYB5CAr004$BMFYB5CAa008$0 (S) -3-Hydroxy-3-methyl-glutaryl-CoA 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6