Doc:Bioactives/Structure

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Size Difference

  • acrylamidine (MW: 72)
  • macrocyclic colubricidin (MW: 2154)
  • tetropetalone-A [1]
  1. Komada T, Sugiyama Y, Abe N, Imachi M, Hirota H, Koshino H, Hirota A (2003) "Revised structure of tetrapetalone A and its absolute stereochemistry" Tetrahedron Lett 44: 7417–7419

New structural types

  • nomofungin
  • TMC-95
  • colubricidin
  • vancoresmycin
  • treponemycin

Re-discovered types

  • mannopeptimycin (from LL-AC98)[1]
  • pristinamycin
  • ziracin
  • daptomycin
  • echinocandin
  • ramoplanin
  • sordarin
  • Mofetil [2]
  1. He H, Williamson RT, Shen B, Graziani EI, Yang HY, Sakya SM, Petersen PJ, Carter GT (2002) "Mannopeptimycins, novel antibacterial glycopeptides from Streptomyces hygroscopicus, LL-AC98" J Am Chem Soc 124: 9729–9736
  2. Chaudhry V, Cornblath DR, Griffin JW, O’Brien R, Drachman DB (2001) "Mycophenolate mofetil: A safe and promising immunosuppressant in neuromuscular diseases" Neurology 56:94-96
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