Category:TP3

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==Saponins==
 
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Saponins are surfactant glycosides, i.e., they produce foams in aqueous solution and therefore are called ‘sapo’ (a Latin for soap).  Plant-based crude drugs are still actively prescribed in Eastern Asia, and many of their active components are attributed to saponins.  Well known examples of saponin and its aglycone include glycyrrhizin from liquorice ([[Species:Glycyrrhiza|''Glycyrrhiza uralensis/glabra'']], [[:Category:Fabaceae]]) used in European confectionery and Asian medicine; ginsenosides from ginseng ([[Species:Panax|''Panax ginseng'']], [[:Category:Araliaceae|Araliaceae]]) for tonic, especially in Korea; diosgenin from wild yam ([[Species:Dioscorea|''Dioscorea spp.'']], [[:Category:Dioscoreaceae|Dioscoreaceae]]) for hormone replacement therapy.
 
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{| style="text-align:center; cellpadding:0"
 
|-
 
| [[Image:2,3-oxidosqualene.png]]<br/>2,3-Oxidosqualene
 
| [[Image:Arrow00r.png]]
 
| [[Image:Dammarane.png]]<br/>{{Bilingual|Dammarane-type|ダンマラン (dammarane) 型}}
 
|-
 
| || || [[Image:Arrow00d35.png]] ring rearrangement
 
|-
 
| [[Image:Lupane.png]]<br/>Lupane-type
 
| [[Image:Arrow00l.png]]
 
| [[Image:Baccharane.png]]<br/>Baccharane-type
 
|-
 
| [[Image:Arrow00d35.png]]
 
|-
 
| [[Image:Oleanane.png]]<br/>Oleanane-type
 
| [[Image:Arrow00r.png]]
 
| [[Image:Taraxastane.png]]<br/>Taraxastane-type
 
|}
 
  
 
==Design of Tri-terpene ID numbers ID番号の設計==
 
==Design of Tri-terpene ID numbers ID番号の設計==

Revision as of 11:52, 3 August 2010

Triterpene (C30) Biosynthesis

Triterpenes are formed by joining two FPPs tail-to-tail. The precursor compound of cholesterol (C27) is lanosterol (C30) for animals. For plants, fungi and algae, it is almost cycloartenol with a trace of lanosterol-derived sterols[1].


Phytosterols

Most common phytosterols are campesterol, β-sitosterol, and stigmasterol. Soybean (Glycine max, Fabaceae) is a rich source of phytosterols (about 0.1% of its weight), and is used for semi-synthesis of medicinal steroids [2]. Since dietary phytosterols reduce cholesterol levels, they are used as food additives such as for margarine [3]. Vitamin D is a family of sterol metabolites generated photochemically in our skin by UV irradiation.


Design of Tri-terpene ID numbers ID番号の設計

12-DIGIT

T P 3 x y y r h g n c c
x ... species information
Symbol at x Kingdom Phyla Examples
I Animalia Arthropoda (Insects, crabs) ecdysteroids
V Chordate (Vertebrates) sex steroids, corticosteroids, anabolic steroids
O Others marine steroids
P Plantae Phytosterols lanosterols, cholesterols, brassinolides
S Saponins saponins
F Fungi ergosterols ergosterols
B Bacteria bacterial sterols hopanoids
y ... backbone structure (母核構造) 
Symbol at y Carbons Steroids
GN C17 gonane Gonane.png
ES C18 estrane Estrane.png
AD C19 androstane Androstane.png
PG C21 pregnane Pregnane.png
CA C24 cholane Cholane.png
CL C27 cholestane Cholestane.png
CM C28 campestane Campestane.png
EG C28 ergostane Ergostane.png
SG C29 (4 rings) stigmastane Stigmastane.png
PR C29 (4 rings) poriferastane Poriferastane.png
Symbol at y Carbons (Plant) Triterpenes
LN C30 (4 rings) lanostane Lanostane.png
CY C30 (4 rings) cycloartane Cycloartane.png
BC C30 (4 rings) baccharane Baccharane.png
CC C30 (4 rings) cucurbitane Cucurbitane.png
DM C30 (4 rings) dammarane Dammarane.png
HL C30 (4 rings) holostane File:Holostane .png
PF C29 (5 rings) pfaffane Pfaffane.png
HP C30 (5 rings) hopane Hopane.png
LP C30 (5 rings) lupane Lupane.png
OL C30 (5 rings) oleanane Oleanane.png
SR C30 (5 rings) serratane Serratane.png
TR C30 (5 rings) taraxastane Taraxastane.png
UR C30 (5 rings) ursane Ursane.png
r ... number of major rings (環構造数) 

Click above categories to see details.

h ... hydroxylation pattern (水酸基数) 

Click above categories to see details.

g ... glycosylation pattern(糖修飾パターン) 

Click above categories to see details.

n ... number of sugars (修飾糖数) 

Click above categories to see details.

c ... serial number (通し番号)

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