Category:Floratheasaponin

Floratheasaponin A-C is known to significantly reduce the amount of neutral lipids (triglycerides) in blood serum for 50-100 mg/kg^[1]. For this activity, acylation at 21 and 22 positions of the triterpene structure is necessary. Chakasaponin I-III inhibits pancreatic lipase and for this activity, the hydroxyl group at position 15 is important. Other functionality of floral saponins are anti-allergy and gastric mucosal protection ^[2].

↑ Yoshikawa M, Morikawa T, Yamamoto K, Kato Y, Nagatomo A, Matsuda H (2005) J Nat Prod 68:1360-1365
↑ Yoshikawa M, Wang T, Sugimoto S, Nakamura S, Nagatomo A, Matsuda H, Harima S (2008) Yakugaku Zasshi 128:141-151

Yoshikawa M, Nakamura S, Kato Y, Matsuhira K, Matsuda H (2007) Chem Pharm Bull 55:598-605
Yoshikawa M, Sugimoto S, Nakamura S, Matsuda H (2008) Chem Pharm Bull 56:1297-1303

Floratheasaponins

Name	R¹	R²	R³	R⁴	R⁵	R⁶
Floratheasaponin A	H	H	Ang	Ac	H	Xyl
Floratheasaponin B	OH	H	Ang	Ang	H	Xyl
Floratheasaponin C	OH	H	Ang	2MB	H	Xyl
Floratheasaponin D	H	H	Ang	Ac	H	Rha
Floratheasaponin E	OH	H	Ang	Ang	H	Rha
Floratheasaponin F	OH	H	Ang	2MB	H	Rha
Floratheasaponin G	H	H	Tig	Ac	H	Rha
Floratheasaponin H	H	Ac	Ang	Ac	H	Rha
Floratheasaponin I	H	H	Ang	H	Ac	Rha
Chakasaponin I	H	H	Tig	Ac	H	Xyl
Chakasaponin II	OH	H	Tig	Tig	H	Xyl
Chakasaponin III	OH	H	Tig	Ac	H	Xyl

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[0] Yoshikawa M, Morikawa T, Yamamoto K, Kato Y, Nagatomo A, Matsuda H (2005) J Nat Prod 68:1360-1365

[1] Yoshikawa M, Wang T, Sugimoto S, Nakamura S, Nagatomo A, Matsuda H, Harima S (2008) Yakugaku Zasshi 128:141-151

[1]

[2]

Category:Floratheasaponin

Floratheasaponins

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