Enzyme:6.3.4.5

Upper Levels: EC6.-.-.- Ligases. : EC6.3.-.- Forming carbon-nitrogen bonds. : EC6.3.4.- Other carbon--nitrogen ligases.

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.3.4.5

L-citrulline:L-aspartate ligase (AMP-forming)
Systematic Name	L-citrulline:L-aspartate ligase (AMP-forming)
Common Name	argininosuccinate synthase citrulline-aspartate ligase argininosuccinate synthetase arginine succinate synthetase argininosuccinic acid synthetase

ATP + L-Aspartic acid + L-Citrulline => AMP + Pyrophosphate + L-Arginino-succinic acid (links: ATP + (2S) -2-Amino-5- (carbamoylamino) pentanoic acid + (2S)-2-aminobutanedioic acid = AMP + 2- [ [N'- [ (4S) -4-Amino-5-hydroxy-5-oxopentyl] carbamimidoyl] amino] butanedioic acid)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0 AMP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 (2S) -2-Amino-5- (carbamoylamino) pentanoic acid <Mapping> AtomMap:BMAXS5AMl004$BMAXS5ANj003$0 2- [ [N'- [ (4S) -4-Amino-5-hydroxy-5-oxopentyl] carbamimidoyl] amino] butanedioic acid 1 ↔ 5 2 ↔ 6 3 ↔ 7 4 ↔ 8 5 ↔ 9 6 ↔ 10 7 ↔ 11 8 ↔ 12 9 ↔ 13 (2S)-2-aminobutanedioic acid <Mapping> AtomMap:BMAAS4CA0003$BMAXS5ANj003$0 2- [ [N'- [ (4S) -4-Amino-5-hydroxy-5-oxopentyl] carbamimidoyl] amino] butanedioic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 14