Enzyme:6.3.2.11

Upper Levels: EC6.-.-.- Ligases. : EC6.3.-.- Forming carbon-nitrogen bonds. : EC6.3.2.- Acid--D-amino-acid ligases (peptide synthases).

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.3.2.11

L-histidine:beta-alanine ligase (AMP-forming)
Systematic Name	L-histidine:beta-alanine ligase (AMP-forming)
Common Name	carnosine synthase carnosine synthetase carnosine-anserine synthetase homocarnosine-carnosine synthetase carnosine-homocarnosine synthetase

ATP + N(pai)-Methyl-L-histidine + beta-Alanine => AMP + L-Anserine + Pyrophosphate (links: ATP + L-Anserine + 3-Amino-propanoic acid = AMP + (2S) -2-Amino-3- (3-methylimidazol-4-yl) propanoic acid + L-Anserine)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0 AMP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 L-Anserine <Mapping> AtomMap:BMAXDP--0011$BMACIZANr002$0 (2S) -2-Amino-3- (3-methylimidazol-4-yl) propanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 3-Amino-propanoic acid <Mapping> AtomMap:BMAAS3AK0001$BMAXDP--0011$1 (2nd) L-Anserine 1 ↔ 11 2 ↔ 12 3 ↔ 13 4 ↔ 14

ATP + L-Arginine + beta-Alanine => AMP + beta-Alanyl-L-arginine + Pyrophosphate (links: ATP + (2S) -2- (3-Aminopropanoylamino) -5- (diaminomethylideneamino) pentanoic acid + 3-Amino-propanoic acid = AMP + L-Arginine + (2S) -2- (3-Aminopropanoylamino) -5- (diaminomethylideneamino) pentanoic acid)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0 AMP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 (2S) -2- (3-Aminopropanoylamino) -5- (diaminomethylideneamino) pentanoic acid <Mapping> AtomMap:BMAXDP--0003$BMAAS5AN0003$0 L-Arginine 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 10 10 ↔ 9 3-Amino-propanoic acid <Mapping> AtomMap:BMAAS3AK0001$BMAXDP--0003$1 (2nd) (2S) -2- (3-Aminopropanoylamino) -5- (diaminomethylideneamino) pentanoic acid 1 ↔ 11 2 ↔ 12 3 ↔ 13 4 ↔ 14

ATP + L-Lysine + beta-Alanine => AMP + beta-Alanyl-L-lysine + Pyrophosphate (links: ATP + beta-Alanyl-L-lysine + 3-Amino-propanoic acid = AMP + (2S) -2,6-Diaminohexanoic acid + beta-Alanyl-L-lysine)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0 AMP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 beta-Alanyl-L-lysine <Mapping> AtomMap:BMAXDP--0004$BMAAS6AN0005$0 (2S) -2,6-Diaminohexanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 3-Amino-propanoic acid <Mapping> AtomMap:BMAAS3AK0001$BMAXDP--0004$1 (2nd) beta-Alanyl-L-lysine 1 ↔ 9 2 ↔ 10 3 ↔ 11 4 ↔ 12

ATP + L-Histidine + beta-Alanine => AMP + L-Carnosine + Pyrophosphate (links: ATP + L-Carnosine + 3-Amino-propanoic acid = AMP + (2S) -2-Amino-3- (1H-imidazol-5-yl) propanoic acid + L-Carnosine)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0 AMP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 L-Carnosine <Mapping> AtomMap:BMAXDP--0012$BMACIZ--0002$0 (2S) -2-Amino-3- (1H-imidazol-5-yl) propanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 3-Amino-propanoic acid <Mapping> AtomMap:BMAAS3AK0001$BMAXDP--0012$1 (2nd) L-Carnosine 1 ↔ 10 2 ↔ 11 3 ↔ 12 4 ↔ 13