Enzyme:1.5.1.7

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.5.-.- Acting on the CH-NH group of donors. : EC1.5.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.5.1.7

N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase(L-lysine-forming)
Systematic Name	N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase(L-lysine-forming)
Common Name	saccharopine dehydrogenase (NAD+, L-lysine-forming) lysine-2-oxoglutarate reductase dehydrogenase, saccharopine (nicotinamide adenine dinucleotide,lysine forming) epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysineforming) N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming)

NAD+ + L-Saccharopine + H2O = NADH + L-Lysine + 2-Oxo-glutaric acid (links: NAD+ + (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid = NADH + (2S) -2,6-Diaminohexanoic acid + 2-Oxo-pentanedioic acid)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid <Mapping> AtomMap:BMAXS6ANk004$BMAAS6AN0005$0 (2S) -2,6-Diaminohexanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid <Mapping> AtomMap:BMAXS6ANk004$BMFYS5DAp005$0 2-Oxo-pentanedioic acid 9 ↔ 4 10 ↔ 3 11 ↔ 2 12 ↔ 1 13 ↔ 5