Enzyme:1.3.1.2

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.3.-.- Acting on the CH-CH group of donors. : EC1.3.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.3.1.2

5,6-dihydrouracil:NADP+ 5-oxidoreductase
Systematic Name	5,6-dihydrouracil:NADP+ 5-oxidoreductase
Common Name	dihydropyrimidine dehydrogenase (NADP+) dihydrothymine dehydrogenase dihydrouracil dehydrogenase (NADP) 4,5-dihydrothymine: oxidoreductase DPD

NADP+ + 5,6-Dihydro-thymine = NADPH + Thymine (links: NADP+ + 5,6-Dihydro-thymine = NADPH + 5-Methyl-1H-pyrimidine-2,4-dione)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 5,6-Dihydro-thymine <Mapping> AtomMap:BMMCPYTY0001$BMMCPYTY0006$0 5-Methyl-1H-pyrimidine-2,4-dione 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 9 ↔ 9

NADP+ + 5,6-Dihydro-uracil = NADPH + Uracil (links: NADP+ + 5,6-Dihydro-uracil = NADPH + 1H-Pyrimidine-2,4-dione)
NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 5,6-Dihydro-uracil <Mapping> AtomMap:BMMCPYUR0004$BMMCPYUR0017$0 1H-Pyrimidine-2,4-dione 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6