Enzyme:1.1.1.21

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.1.-.- Acting on the CH-OH group of donors. : EC1.1.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.1.1.21

alditol:NAD(P)+ 1-oxidoreductase
Systematic Name	alditol:NAD(P)+ 1-oxidoreductase
Common Name	aldehyde reductase aldose reductase polyol dehydrogenase (NADP+) ALR2 alditol:NADP oxidoreductase

NADP+ + Glycerol = NADPH + D-Glyceraldehyde (links: NADP+ + Propane-1,2,3-triol = NADPH + D-Glyceraldehyde)
NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 Propane-1,2,3-triol <Mapping> AtomMap:BMFYS3HOq011$BMFYS3ALq008$0 D-Glyceraldehyde 1 ↔ 1 2 ↔ 2 3 ↔ 3

NADP+ + D-Sorbitol = NADPH + D-Glucose (links: NADP+ + (2R,3R,4R,5S) -Hexane-1,2,3,4,5,6-hexol = NADPH + D-Glucose)
NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2R,3R,4R,5S) -Hexane-1,2,3,4,5,6-hexol <Mapping> AtomMap:BMSUM6H0--02$BMSUM6A0--06$0 D-Glucose 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6

NADP+ + Galactitol = NADPH + D-Galactose (links: NADP+ + (2S,3R,4S,5R) -Hexane-1,2,3,4,5,6-hexol = NADPH + (3R,4S,5R,6R) -6- (Hydroxymethyl) oxane-2,3,4,5-tetrol)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2S,3R,4S,5R) -Hexane-1,2,3,4,5,6-hexol <Mapping> AtomMap:BMSUM6H0--03$BMSUM6A0--05$0 (3R,4S,5R,6R) -6- (Hydroxymethyl) oxane-2,3,4,5-tetrol 1 ↔ 6 2 ↔ 5 3 ↔ 4 4 ↔ 3 5 ↔ 2 6 ↔ 1

NADP+ + Xylitol = NADPH + D-Xylose (links: NADP+ + (2S,3S,4R) -Pentane-1,2,3,4,5-pentol = NADPH + (2R,3S,4R) -Oxane-2,3,4,5-tetrol)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2S,3S,4R) -Pentane-1,2,3,4,5-pentol <Mapping> AtomMap:BMSUM5H0--04$BMSUM5A0--07$0 (2R,3S,4R) -Oxane-2,3,4,5-tetrol 1 ↔ 5 2 ↔ 4 3 ↔ 3 4 ↔ 2 5 ↔ 1

NADP+ + L-Arabitol = NADPH + L-Arabinose (links: NADP+ + L-Arabitol = NADPH + Oxane-2,3,4,5-tetrol)
NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 L-Arabitol <Mapping> AtomMap:BMSUM5X0--01$BMSUM5A0--09$0 Oxane-2,3,4,5-tetrol 1 ↔ 5 2 ↔ 4 3 ↔ 3 4 ↔ 2 5 ↔ 1