Enzyme:1.5.1.8

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.5.-.- Acting on the CH-NH group of donors. : EC1.5.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.5.1.8

N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase(L-lysine-forming)
Systematic Name	N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase(L-lysine-forming)
Common Name	saccharopine dehydrogenase (NADP+, L-lysine-forming) lysine-2-oxoglutarate reductase lysine-ketoglutarate reductase L-lysine-alpha-ketoglutarate reductase lysine:alpha-ketoglutarate:TPNH oxidoreductase(epsilon-N-[gultaryl-2]-L-lysine forming)

NADPH + L-Lysine + 2-Oxo-glutaric acid => NADP+ + L-Saccharopine + H2O (links: NADP+ + (2S) -2,6-Diaminohexanoic acid + 2-Oxo-pentanedioic acid = NADPH + (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2S) -2,6-Diaminohexanoic acid <Mapping> AtomMap:BMAXS6ANk004$BMAAS6AN0005$0 (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 2-Oxo-pentanedioic acid <Mapping> AtomMap:BMFYS5DAp005$BMAXS6ANk004$1 (2nd) (2S) -2- [ [ (5S) -5-Amino-6-hydroxy-6-oxohexyl] amino] pentanedioic acid 1 ↔ 13 2 ↔ 9 3 ↔ 10 4 ↔ 11 5 ↔ 12