| Aspergillus nidulans FGSC A4 (GenBank XP_658638) all species
|
| Class
|
NRPKS (length: 2793) all classes Class in KS domain phylogeny
|
Reliability
|
verified
|
| Product
|
asperfuranone
|
GeneName
|
pks13(afoE)
|
| UniProt,UniRef90
|
C8VTX9 , C8VTX9
|
UniRef50
|
C8VTX9
|
| Domain by MAPSI
|
KS-AT-ACP
(notation help / all patterns)
|
| Domain by CDD
|
KS-AT-PP-ME-TE
(notation help / all patterns)
|
| Domain by ITER-DB
|
KS-AT-ACP
(notation help / all patterns)
|
| Estimated Domain
|
SAT-KS-AT-PT-ACP-ME-R
|
| Description
|
hypothetical protein AN1034.2 [Aspergillus nidulans FGSC A4]
|
| Information
|
Putative polyketide synthase; required for asperfuranone biosynthesis; transcriptionally induced by scrP overexpression.
|
| References
|
- Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC: Illuminating the diversity of aromatic polyketide synthases in aspergillus nidulans. J Am Chem Soc, 2012
- Andersen M R, Nielsen J B, Klitgaard A, Petersen L M, Zachariasen M, Hansen T J, Blicher L H, Gotfredsen C H, Larsen T O, Nielsen K F, Mortensen U H: Accurate prediction of secondary metabolite gene clusters in filamentous fungi. Proc Natl Acad Sci U S A 110(1): E99-107. 2013
- Chiang YM, Szewczyk E, Davidson AD, Keller N, Oakley BR, Wang CC: A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in aspergillus nidulans. J Am Chem Soc 131(8):2965-2970, 2009
- Fisch KM, Gillaspy AF, Gipson M, Henrikson JC, Hoover AR, Jackson L, Najar FZ, Wagele H, Cichewicz RH: Chemical induction of silent biosynthetic pathway transcription in aspergillus niger. J Ind Microbiol Biotechnol 36(9):1199-1213, 2009
|
| Link
|
AspGD
|
This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)
