PKS:AN1036

Aspergillus nidulans FGSC A4 (GenBank XP_658640) all species
Class	RPKS (length: 2527) all classes Class in KS domain phylogeny	Reliability	verified
Product	asperfuranone	GeneName	afoG
UniProt,UniRef90	C8VTX6 , C8VTX6	UniRef50	C8VTX6
Domain by MAPSI	KS-AT-DH-ER-KR-ACP (notation help / all patterns)
Domain by CDD	KS-AT-DH-ME-ER-KR-PP (notation help / all patterns)
Domain by ITER-DB	{{{ITERDB}}} (notation help / all patterns)
Estimated Domain
Description	hypothetical protein AN1036.2 [Aspergillus nidulans FGSC A4]
Information	Putative polyketide synthase; required for asperfuranone biosynthesis; transcriptionally induced by scrP overexpression
References	Andersen M R, Nielsen J B, Klitgaard A, Petersen L M, Zachariasen M, Hansen T J, Blicher L H, Gotfredsen C H, Larsen T O, Nielsen K F, Mortensen U H: Accurate prediction of secondary metabolite gene clusters in filamentous fungi. Proc Natl Acad Sci U S A 110(1): E99-107. 2013 Castoe TA, Stephens T, Noonan BP, Calestani C: A novel group of type I polyketide synthases (PKS) in animals and the complex phylogenomics of PKSs. Gene 392:47-58, 2007 Fisch KM, Gillaspy AF, Gipson M, Henrikson JC, Hoover AR, Jackson L, Najar FZ, Wagele H, Cichewicz RH: Chemical induction of silent biosynthetic pathway transcription in aspergillus niger. J Ind Microbiol Biotechnol 36(9):1199-1213, 2009
Link	AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)