| Glarea lozoyensis (GenBank AAN59953) all species
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| Class
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NRPKS (length: 2124) all classes Class 11.NRPKS_I(4a)melanin in KS domain phylogeny
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Reliability
|
identified
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| Product
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melanin
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GeneName
|
pks1
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| UniProt,UniRef90
|
[1] , [2]
|
UniRef50
|
[3]
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| Domain by MAPSI
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KS-AT-ACP-ACP-CYC
(notation help / all patterns)
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| Domain by CDD
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KS-AT-PP-PP-TE
(notation help / all patterns)
|
| Domain by ITER-DB
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{{{ITERDB}}}
(notation help / all patterns)
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| Estimated Domain
|
|
| Description
|
polyketide synthase 1 [Glarea lozoyensis]
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| Information
|
required for melanin synthesis.Inferred domain architecture: SAT-KS-AT-PT-ACP-ACP-TE/CLC
|
| References
|
- Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC: Illuminating the diversity of aromatic polyketide synthases in aspergillus nidulans. J Am Chem Soc, 2012
- Fisch KM, Gillaspy AF, Gipson M, Henrikson JC, Hoover AR, Jackson L, Najar FZ, Wagele H, Cichewicz RH: Chemical induction of silent biosynthetic pathway transcription in aspergillus niger. J Ind Microbiol Biotechnol 36(9):1199-1213, 2009
- Li Y, Image, II, Xu W, Image I, Tang Y: Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem 285(30):22764-22773, 2010
- Valarmathi R, Hariharan GN, Venkataraman G, Parida A: Characterization of a non-reducing polyketide synthase gene from lichen dirinaria applanata. Phytochemistry 70(6):721-729, 2009
- Varga J, Rigo K, Kocsube S, Farkas B, Pal K: Diversity of polyketide synthase gene sequences in Aspergillus species. Res Microbiol 154:593-600, 2003
- Zhang A, Lu P, Dahl-Roshak AM, Paress PS, Kennedy S, Tkacz JS and An Z: Efficient disruption of a polyketide synthase gene ( pks1) required for melanin synthesis through agrobacterium-mediated transformation of glarea lozoyensis. Mol Genet Genomics 268(5):645-655, 2003
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| Link
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AspGD
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This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)
