Enzyme:6.3.5.4

Upper Levels: EC6.-.-.- Ligases. : EC6.3.-.- Forming carbon-nitrogen bonds. : EC6.3.5.- Carbon--nitrogen ligases with glutamine as amido-N-donor.

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.3.5.4

L-aspartate:L-glutamine amido-ligase (AMP-forming)
Systematic Name	L-aspartate:L-glutamine amido-ligase (AMP-forming)
Common Name	asparagine synthase (glutamine-hydrolysing) asparagine synthetase (glutamine-hydrolysing)

ATP + L-Glutamine + L-Aspartic acid + H2O => AMP + L-Glutamic acid + L-Asparagine + Pyrophosphate (links: L-Glutamine + (2S)-2-aminobutanedioic acid + ATP = (2S) -2-Amino-pentanedioic acid + (S) -2,4-Diamino-4-oxobutanoic acid + AMP)

L-Glutamine <Mapping> AtomMap:BMAAS5CA0007$BMAAS5AM0002$0 (2S) -2-Amino-pentanedioic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 (2S)-2-aminobutanedioic acid <Mapping> AtomMap:BMAAS4AM0002$BMAAS4CA0003$0 (S) -2,4-Diamino-4-oxobutanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0021$0 AMP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 L-Glutamine <Mapping> AtomMap:BMAAS5AM0002$BMAAS4AM0002$0 (S) -2,4-Diamino-4-oxobutanoic acid 7 ↔ 6