Enzyme:6.3.1.8

Upper Levels: EC6.-.-.- Ligases. : EC6.3.-.- Forming carbon-nitrogen bonds. : EC6.3.1.- Acid--ammonia (or amide) ligases (amide synthases).

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.3.1.8

gamma-L-Glutamyl-L-cysteinyl-glycine:spermidine ligase(ADP-forming) [spermidine is numbered so that atom N-1 is in theamino group of the aminopropyl part of the molecule]
Systematic Name	gamma-L-Glutamyl-L-cysteinyl-glycine:spermidine ligase(ADP-forming) [spermidine is numbered so that atom N-1 is in theamino group of the aminopropyl part of the molecule]
Common Name	glutathionylspermidine synthase glutathione:spermidine ligase (ADP-forming)

ATP + Glutathione + Spermidine => ADP + N1-(g-L-glutamyl-L-cysteinyl-glycyl)-spermidine + Orthophosphate (links: ATP + Glutathione + N1- (g-L-glutamyl-L-cysteinyl-glycyl) -spermidine = ADP + N1- (g-L-glutamyl-L-cysteinyl-glycyl) -spermidine + N- (3-Aminopropyl) butane-1,4-diamine)

ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0020$0 ADP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 Glutathione <Mapping> AtomMap:BMAXTP--0003$BMAXTP--m007$1 (2nd) N1- (g-L-glutamyl-L-cysteinyl-glycyl) -spermidine 1 ↔ 19 2 ↔ 20 3 ↔ 21 4 ↔ 22 5 ↔ 23 6 ↔ 24 7 ↔ 14 8 ↔ 15 9 ↔ 16 10 ↔ 17 11 ↔ 18 12 ↔ 11 13 ↔ 12 14 ↔ 13 N1- (g-L-glutamyl-L-cysteinyl-glycyl) -spermidine <Mapping> AtomMap:BMAXTP--m007$BMFYB4ANm012$0 N- (3-Aminopropyl) butane-1,4-diamine 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10