Enzyme:2.3.1.85

Upper Levels: EC2.-.-.- Transferases. : EC2.3.-.- Acyltransferases. : EC2.3.1.- Transferring groups other than amino-acyl groups.

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.3.1.85

acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-and enoyl-reducing and thioester-hydrolysing)
Systematic Name	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-and enoyl-reducing and thioester-hydrolysing)
Common Name	fatty-acid synthase yeast fatty acid synthase

2 NADPH + Hexanoyl-CoA + Malonyl-CoA = 2 NADP+ + 2 CoA + CO2 + Octanoic acid (links: NADP+ + Hexanoyl-CoA + Malonyl-CoA + CO2 = NADPH + CoA + Malonyl-CoA + Octanoic acid)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 Hexanoyl-CoA <Mapping> AtomMap:BMFYS6ESa003$BMCCPUAPf023$0 CoA 8 ↔ 1 9 ↔ 2 10 ↔ 3 11 ↔ 4 12 ↔ 5 13 ↔ 6 14 ↔ 7 15 ↔ 8 16 ↔ 9 17 ↔ 10 18 ↔ 11 19 ↔ 12 20 ↔ 13 21 ↔ 14 22 ↔ 15 39 ↔ 32 40 ↔ 33 41 ↔ 35 42 ↔ 34 43 ↔ 36 44 ↔ 37 45 ↔ 38 46 ↔ 39 47 ↔ 40 48 ↔ 41 49 ↔ 42 50 ↔ 43 51 ↔ 44 52 ↔ 45 Malonyl-CoA <Mapping> AtomMap:BMFYS3CAa020$BMCCPUAPf023$0 CoA 7 ↔ 1 8 ↔ 2 9 ↔ 3 10 ↔ 4 11 ↔ 5 12 ↔ 6 13 ↔ 7 14 ↔ 8 15 ↔ 9 16 ↔ 10 17 ↔ 11 18 ↔ 12 19 ↔ 13 20 ↔ 14 21 ↔ 15 38 ↔ 32 39 ↔ 33 40 ↔ 35 41 ↔ 34 42 ↔ 36 43 ↔ 37 44 ↔ 38 45 ↔ 39 46 ↔ 40 47 ↔ 41 48 ↔ 42 49 ↔ 43 50 ↔ 44 51 ↔ 45 CO2 <Mapping> AtomMap:BMXXSX--0007$BMFYS3CAa020$0 Malonyl-CoA 1 ↔ 1 Malonyl-CoA <Mapping> AtomMap:BMFYS3CAa020$BMFYS8CA0002$0 Octanoic acid 2 ↔ 2 3 ↔ 1 Hexanoyl-CoA <Mapping> AtomMap:BMFYS6ESa003$BMFYS8CA0002$0 Octanoic acid 1 ↔ 3 2 ↔ 4 3 ↔ 5 4 ↔ 6 5 ↔ 7 6 ↔ 8

2 NADPH + Butanoyl-CoA + Malonyl-CoA = 2 NADP+ + 2 CoA + CO2 + Hexanoic acid (links: NADP+ + CoA + Malonyl-CoA + CO2 + Butanoyl-CoA = NADPH + Butanoyl-CoA + CoA + Malonyl-CoA + Hexanoic acid)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 CoA <Mapping> AtomMap:BMCCPUAPf023$BMFYS4ESa005$0 Butanoyl-CoA 1 ↔ 6 2 ↔ 7 3 ↔ 8 4 ↔ 9 5 ↔ 10 6 ↔ 11 7 ↔ 12 8 ↔ 13 9 ↔ 14 10 ↔ 15 11 ↔ 16 12 ↔ 17 13 ↔ 18 14 ↔ 19 15 ↔ 20 32 ↔ 37 33 ↔ 38 34 ↔ 39 35 ↔ 40 36 ↔ 41 37 ↔ 42 38 ↔ 43 39 ↔ 44 40 ↔ 45 41 ↔ 46 42 ↔ 47 43 ↔ 48 44 ↔ 49 45 ↔ 50 Malonyl-CoA <Mapping> AtomMap:BMFYS3CAa020$BMCCPUAPf023$0 CoA 7 ↔ 1 8 ↔ 2 9 ↔ 3 10 ↔ 4 11 ↔ 5 12 ↔ 6 13 ↔ 7 14 ↔ 8 15 ↔ 9 16 ↔ 10 17 ↔ 11 18 ↔ 12 19 ↔ 13 20 ↔ 14 21 ↔ 15 38 ↔ 32 39 ↔ 33 40 ↔ 35 41 ↔ 34 42 ↔ 36 43 ↔ 37 44 ↔ 38 45 ↔ 39 46 ↔ 40 47 ↔ 41 48 ↔ 42 49 ↔ 43 50 ↔ 44 51 ↔ 45 CO2 <Mapping> AtomMap:BMXXSX--0007$BMFYS3CAa020$0 Malonyl-CoA 1 ↔ 1 Malonyl-CoA <Mapping> AtomMap:BMFYS3CAa020$BMFYS6CA0014$0 Hexanoic acid 2 ↔ 2 3 ↔ 1 Butanoyl-CoA <Mapping> AtomMap:BMFYS4ESa005$BMFYS6CA0014$0 Hexanoic acid 1 ↔ 3 2 ↔ 4 3 ↔ 5 4 ↔ 6