Enzyme:2.1.2.3

Upper Levels: EC2.-.-.- Transferases. : EC2.1.-.- Transferring one-carbon groups. : EC2.1.2.- Hydroxymethyl-, formyl- and related transferases.

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.1.2.3

10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase
Systematic Name	10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase
Common Name	phosphoribosylaminoimidazolecarboxamide formyltransferase 5-amino-4-imidazolecarboxamide ribonucleotide transformylase AICAR transformylase 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase

10-Formyl-tetrahydro-folic acid + 5'-Phospho-ribosyl-4-carboxamido-5-amino-imidazole => L-Tetrahydro-folic acid + 5'-Phospho-ribosyl-4-carboxamido-5-formamido-imidazole (links: 10-Formyl-tetrahydro-folic acid + 1- (5'-Phosphoribosyl) -5-amino-4-imidazolecarboxamide = L-Tetrahydro-folic acid + [(2R,3S,4R,5R) -5- (4-Carbamoyl-5-formamidoimidazol-1-yl) -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate)

10-Formyl-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOo001$BMCCPTFO0013$0 L-Tetrahydro-folic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 16 ↔ 16 17 ↔ 17 18 ↔ 18 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 10-Formyl-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOo001$BMMCIZ--S529$0 [(2R,3S,4R,5R) -5- (4-Carbamoyl-5-formamidoimidazol-1-yl) -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate 27 ↔ 9 1- (5'-Phosphoribosyl) -5-amino-4-imidazolecarboxamide <Mapping> AtomMap:BMMCIZ--S528$BMMCIZ--S529$0 [(2R,3S,4R,5R) -5- (4-Carbamoyl-5-formamidoimidazol-1-yl) -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 12 10 ↔ 13 11 ↔ 14 12 ↔ 15 13 ↔ 16