Enzyme:2.1.1.45

Upper Levels: EC2.-.-.- Transferases. : EC2.1.-.- Transferring one-carbon groups. : EC2.1.1.- Methyltransferases.

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.1.1.45

5,10-methylenetetrahydrofolate:dUMP C-methyltransferase
Systematic Name	5,10-methylenetetrahydrofolate:dUMP C-methyltransferase
Common Name	thymidylate synthase dTMP synthase thymidylate synthetase methylenetetrahydrofolate:dUMP C-methyltransferase TMP synthetase

dUMP + 5,10-Methylene-tetrahydro-folic acid => dTMP + 7,8-Dihydro-folic acid (links: dUMP + 5,10-Methylene-tetrahydro-folic acid = dTMP + 7,8-Dihydro-folic acid)

dUMP <Mapping> AtomMap:BMMCPYUR0010$BMMCPYTY0003$0 dTMP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 9 ↔ 10 10 ↔ 11 11 ↔ 12 12 ↔ 13 13 ↔ 14 5,10-Methylene-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOs005$BMCCPTFO0011$0 7,8-Dihydro-folic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 9 15 ↔ 14 16 ↔ 19 17 ↔ 18 18 ↔ 17 19 ↔ 16 20 ↔ 15 21 ↔ 20 22 ↔ 21 23 ↔ 22 24 ↔ 23 25 ↔ 24 26 ↔ 25 27 ↔ 26 5,10-Methylene-tetrahydro-folic acid <Mapping> AtomMap:BMCCPTFOs005$BMMCPYTY0003$0 dTMP 9 ↔ 9