Enzyme:1.2.1.1

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.2.-.- Acting on the aldehyde or oxo group of donors. : EC1.2.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.2.1.1

formaldehyde:NAD+ oxidoreductase (glutathione-formylating)
Systematic Name	formaldehyde:NAD+ oxidoreductase (glutathione-formylating)
Common Name	formaldehyde dehydrogenase (glutathione) NAD-linked formaldehyde dehydrogenase formic dehydrogenase

NAD+ + Glutathione + (R)-Lactaldehyde = NADH + (R)-S-Lactoyl-glutathione (links: NAD+ + Glutathione +  (R) -Lactaldehyde = NADH +  (R) -S-Lactoyl-glutathione)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 Glutathione <Mapping> AtomMap:BMAXTP--0003$BMAXTP--0001$0 (R) -S-Lactoyl-glutathione 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 (R) -Lactaldehyde <Mapping> AtomMap:BMFYS3ALq001$BMAXTP--0001$0 (R) -S-Lactoyl-glutathione 1 ↔ 15 2 ↔ 16 3 ↔ 17

NAD+ + Glutathione + Formaldehyde = NADH + S-Formyl-glutathione (links: NAD+ + Glutathione + Formaldehyde = NADH + S-Formyl-glutathione)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 Glutathione <Mapping> AtomMap:BMAXTP--0003$BMAXTP--o008$0 S-Formyl-glutathione 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 Formaldehyde <Mapping> AtomMap:BMFYS1AL0001$BMAXTP--o008$0 S-Formyl-glutathione 1 ↔ 15