Enzyme:1.14.11.8

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.14.-.- Acting on paired donors, with incorporation or reduction of : EC1.14.11.- With 2-oxoglutarate as one donor, and incorporation of one

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.14.11.8

N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase(3-hydroxylating)
Systematic Name	N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase(3-hydroxylating)
Common Name	trimethyllysine dioxygenase trimethyllysine alpha-ketoglutarate dioxygenase TML-alpha-ketoglutarate dioxygenase TML hydroxylase

N6,N6,N6-Trimethyl-L-lysine + 2-Oxo-glutaric acid + O2 => 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinic acid + CO2 (links: N6,N6,N6-Trimethyl-L-lysine + 2-Oxo-pentanedioic acid = [(5S) -5-Amino-4,6-dihydroxy-6-oxohexyl] -trimethylazanium + Butanedioic acid + CO2)
N6,N6,N6-Trimethyl-L-lysine <Mapping> AtomMap:BMAXS6ANr005$BMAXS6ANq001$0 [(5S) -5-Amino-4,6-dihydroxy-6-oxohexyl] -trimethylazanium 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 11 10 ↔ 10 11 ↔ 9 2-Oxo-pentanedioic acid <Mapping> AtomMap:BMFYS5DAp005$BMFYS4DA0015$0 Butanedioic acid 2 ↔ 4 3 ↔ 3 4 ↔ 2 5 ↔ 1 2-Oxo-pentanedioic acid <Mapping> AtomMap:BMXXSX--0007$BMFYS5DAp005$0 CO2 1 ↔ 1