Enzyme:1.1.1.85

Basic Metabolism Top (代謝トップ)

Molecule Index (化合物索引)

EC classes ( EC分類)

Input New Data (新規入力)

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.1.-.- Acting on the CH-OH group of donors. : EC1.1.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.1.1.85

3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase
Systematic Name	3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase
Common Name	3-isopropylmalate dehydrogenase beta-isopropylmalic enzyme threo-D(s)-3-isopropylmalate dehydrogenase

NAD+ + 3-Carboxy-2-hydroxy-4-methyl-pentanoic acid => NADH + 4-Methyl-2-oxo-pentanoic acid + CO2 (links: NAD+ + (2R,3S) -2-Hydroxy-3-propan-2-ylbutanedioic acid = NADH + 4-Methyl-2-oxo-pentanoic acid + CO2)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2R,3S) -2-Hydroxy-3-propan-2-ylbutanedioic acid <Mapping> AtomMap:BMFYB4DAs011$BMFYB4CAr013$0 4-Methyl-2-oxo-pentanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 (2R,3S) -2-Hydroxy-3-propan-2-ylbutanedioic acid <Mapping> AtomMap:BMFYB4DAs011$BMXXSX--0007$0 CO2 7 ↔ 1

NAD+ + 3-Carboxy-2-hydroxy-4-methyl-pentanoic acid => NADH + 3-Carboxy-4-methyl-2-oxo-pentanoic acid (links: NAD+ + (2R,3S) -2-Hydroxy-3-propan-2-ylbutanedioic acid = NADH + 2-Oxo-3-propan-2-ylbutanedioic acid)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2R,3S) -2-Hydroxy-3-propan-2-ylbutanedioic acid <Mapping> AtomMap:BMFYB4DAs011$BMFYB4DAs013$0 2-Oxo-3-propan-2-ylbutanedioic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7