Enzyme:1.1.1.31

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.1.-.- Acting on the CH-OH group of donors. : EC1.1.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.1.1.31

3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase
Systematic Name	3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase
Common Name	3-hydroxyisobutyrate dehydrogenase beta-hydroxyisobutyrate dehydrogenase

NADH + (S)-Methyl-malonate semialdehyde => NAD+ + (S)-3-Hydroxy-2-methyl-propanoic acid (links: NAD+ +  (2S) - 2-Methyl-3-oxopropanoic acid = NADH +  (2S) -3-Hydroxy-2-methylpropanoic acid)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (2S) - 2-Methyl-3-oxopropanoic acid <Mapping> AtomMap:BMFYB3SAr001$BMFYB3CAr006$0 (2S) -3-Hydroxy-2-methylpropanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4