Category:BMAA
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Upper classes : BM Basic Metabolites
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BMAA: Amino Acids
<p> Proteins are constituted from 20 amino acids. An amino acid has a carbon connected by an amino group and a carboxyl group (called an alpha carbon).
</p>| Straight Class | |||||
|---|---|---|---|---|---|
| BMAAS2 | Straight length 2 Gly 
|
BMAAS3 | Straight length 3 Ser, Cys, Ala 
|
BMAAS4 | Straight length 4 Asp, Asn, Thr 
|
| BMAAS5 | Straight length 5 Gln, Glu 
|
BMAAS6 | Straight length 6 Lys 
|
||
| Branched Class | |||||
| BMAAB4 | Branched length 4 Val, Met 
|
BMAAB5 | Branched length 5 Arg, Leu, Ile 
|
BMAAB6 | Branched length 6
|
| BMAACC | Cyclic Phe, Tyr, Trp, His, Pro 120px |
||||
| Name | Code | Symbol | Structure | Character | pI | Required? |
|---|---|---|---|---|---|---|
| alanine | Ala | A | -CH3 | neutral | 6.0 | |
| serine | Ser | S | -CH2OH | neutral | 5.7 | |
| threonine | Thr | T | -CH(OH)CH3 | neutral | 5.6 | ○ |
| valine | Val | V | -CH(CH3)2 | neutral, branched | 6.0 | ○ |
| leucine | Leu | L | -CH2CH(CH3)2 | neutral, branched | 6.0 | ○ |
| isoleucine | Ile | I | -CH(CH3)CH2CH3 | neutral, branched | 6.0 | ○ |
| aspartic acid | Asp | D | -CH2COOH | acidic | 2.8 | |
| glutamic acid | Glu | E | -CH2CH2COOH | acidic | 3.2 | |
| asparagine | Asn | N | -CH2CONH2 | acidic, amido | 5.4 | |
| glutamine | Gln | Q | -CH2CH2CONH2 | acidic, amido | 5.7 | |
| lysine | Lys | K | -(CH2)4NH2 | basic | 9.7 | ○ |
| arginine | Arg | R | -(CH2)3NHC(=NH)NH2 | basic | 10.8 | |
| cysteine | Cys | C | -CH2SH | neutral, S | 5.1 | |
| methionine | Met | M | -(CH2)2SCH3 | neutral, S | 5.7 | ○ |
| phenylalanine | Phe | F | -CH2-Benz | neutral, aromatic | 5.5 | ○ |
| tyrosine | Tyr | Y | -CH2-Benz-OH | neutral, aromatic | 5.7 | |
| tryptophan | Trp | W | -CH2-Indole | neutral, aromatic | 5.9 | ○ |
| histidine | His | H | -CH2-Imidazole | basic, atomatic | 7.6 | ○ |
| proline | Pro | P | -NH-(CH2)3- | neutral, cyclic, 2nd amine | 6.2 |
D and L in Amino Acid
Definition
Except for Glycine, all amino acids contain chiral carbons, distinguished by D or L (R or S). In the Fischer projection, which places the carboxyl group upward and amino acid-specific branch downward, the amino group must comes either left or right, protruding from the paper plane. If the hydrogen is left and amino group is right, the amino acid is called D, after D-glyceraldehide. If the amino group is left, it is called L.
DL and RS do not coincide
In the Cahn-Ingold-Prelog (or RS) notation, 19 L-amino acids become S-form (when H is placed behind the paper plane, the amino group, carboxyl group and side chain are arranged anticlockwise). Only L-cysteine becomes R-form because S in the side chain makes the arrangement in the order of the amino group, side chain, and carboxyl group. For this reason, although its tetrapodal configuration is the same as the rest of amino acids, it takes R-form. For the same reason, cystine is also R-form.
Glycine has no chiral carbon
Glycine has two Hydrogen branches and therefore not chiral. The amino group of proline is included in the ring sturucture and therefore secondary amine.
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