Enzyme:6.3.5.3

Upper Levels: EC6.-.-.- Ligases. : EC6.3.-.- Forming carbon-nitrogen bonds. : EC6.3.5.- Carbon--nitrogen ligases with glutamine as amido-N-donor.

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.3.5.3

5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase(ADP-forming)
Systematic Name	5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase(ADP-forming)
Common Name	phosphoribosylformylglycinamidine synthase phosphoribosylformylglycinamidine synthetase formylglycinamide ribonucloetide amidotransferase phosphoribosylformylglycineamidine synthetase FGAM synthetase

ATP + 5'-Phospho-ribosyl-N-formyl-glycinamide + L-Glutamine + H2O => ADP + 5'-Phospho-ribosyl-N-formyl-glycinamidine + L-Glutamic acid + Orthophosphate (links: L-Glutamine + ATP + [(2R,5R) -5- [(2-Formamidoacetyl) amino] -3,4-dihydroxyoxolan-2-yl] methyldihydrogen phosphate = (2S) -2-Amino-pentanedioic acid + ADP + [(2R,3S,4R,5R) -5- [(1-Amino-2-formamidoethylidene) amino] -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate)

L-Glutamine <Mapping> AtomMap:BMAAS5CA0007$BMAAS5AM0002$0 (2S) -2-Amino-pentanedioic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 ATP <Mapping> AtomMap:BMCCPUAP0022$BMCCPUAP0020$0 ADP 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 [(2R,5R) -5- [(2-Formamidoacetyl) amino] -3,4-dihydroxyoxolan-2-yl] methyldihydrogen phosphate <Mapping> AtomMap:BMAXS2AMS503$BMFYB2AMS501$0 [(2R,3S,4R,5R) -5- [(1-Amino-2-formamidoethylidene) amino] -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate 1 ↔ 6 2 ↔ 7 3 ↔ 8 4 ↔ 9 5 ↔ 10 6 ↔ 5 7 ↔ 4 8 ↔ 3 9 ↔ 2 10 ↔ 1 L-Glutamine <Mapping> AtomMap:BMAAS5AM0002$BMFYB2AMS501$0 [(2R,3S,4R,5R) -5- [(1-Amino-2-formamidoethylidene) amino] -3,4-dihydroxyoxolan-2-yl] methyl dihydrogen phosphate 7 ↔ 11