Enzyme:1.14.16.4

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.14.-.- Acting on paired donors, with incorporation or reduction of : EC1.14.16.- With reduced pteridine as one donor, and incorporation of one

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.14.16.4

L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase(5-hydroxylating)
Systematic Name	L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase(5-hydroxylating)
Common Name	tryptophan 5-monooxygenase L-tryptophan hydroxylase indoleacetic acid-5-hydroxylase

L-Tryptophan + 5,6,7,8-Tetrahydro-biopterin + O2 => 5-Hydroxy-L-tryptophan + 6,7-Dihydro-biopterin + H2O (links: 2-Amino-6- [(1R,2S) -1,2-dihydroxypropyl] -6,7-dihydro-1H-pteridin-4-one + (2S) -2-Amino-3- (1H-indol-3-yl) propanoic acid = 5,6,7,8-Tetrahydro-biopterin + (2S) -2-Amino-3- (5-hydroxy-1H-indol-3-yl) propanoic acid)

2-Amino-6- [(1R,2S) -1,2-dihydroxypropyl] -6,7-dihydro-1H-pteridin-4-one <Mapping> AtomMap:BMCCPTPTq010$BMCCPTPTq007$0 5,6,7,8-Tetrahydro-biopterin 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 (2S) -2-Amino-3- (1H-indol-3-yl) propanoic acid <Mapping> AtomMap:BMACID--0003$BMACIDHO0001$0 (2S) -2-Amino-3- (5-hydroxy-1H-indol-3-yl) propanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13