Enzyme:1.1.1.222

Upper Levels: EC1.-.-.- Oxidoreductases. : EC1.1.-.- Acting on the CH-OH group of donors. : EC1.1.1.- With NAD(+) or NADP(+) as acceptor.

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.1.1.222

(R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase
Systematic Name	(R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase
Common Name	(R)-4-hydroxyphenyllactate dehydrogenase (R)-aromatic lactate dehydrogenase D-hydrogenase, D-aryllactate

NAD+ + (R)-3-(4-Hydroxy-phenyl)-lactic acid = NADH + 4-Hydroxy-phenyl-pyruvic acid (links: NAD+ +  (R) -3- (4-Hydroxy-phenyl) -lactic acid = NADH + 3- (4-Hydroxyphenyl) -2-oxopropanoic acid)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (R) -3- (4-Hydroxy-phenyl) -lactic acid <Mapping> AtomMap:BMMCBZ2Pk002$BMMCBZ2Pk032$0 3- (4-Hydroxyphenyl) -2-oxopropanoic acid 1 ↔ 9 2 ↔ 8 3 ↔ 7 4 ↔ 1 5 ↔ 6 6 ↔ 5 7 ↔ 4 8 ↔ 3 9 ↔ 2

NADP+ + Phenyl-lactic acid = NADPH + Phenyl-pyruvic acid (links: NADP+ + Phenyl-lactic acid = NADPH + 2-Oxo-3-phenylpropanoic acid)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 Phenyl-lactic acid <Mapping> AtomMap:BMMCBZ1Sk046$BMMCBZ1Sj049$0 2-Oxo-3-phenylpropanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9

NADP+ + (R)-3-(4-Hydroxy-phenyl)-lactic acid = NADPH + 4-Hydroxy-phenyl-pyruvic acid (links: NADP+ +  (R) -3- (4-Hydroxy-phenyl) -lactic acid = NADPH + 3- (4-Hydroxyphenyl) -2-oxopropanoic acid)

NADP+ <Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0 NADPH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 (R) -3- (4-Hydroxy-phenyl) -lactic acid <Mapping> AtomMap:BMMCBZ2Pk002$BMMCBZ2Pk032$0 3- (4-Hydroxyphenyl) -2-oxopropanoic acid 1 ↔ 9 2 ↔ 8 3 ↔ 7 4 ↔ 1 5 ↔ 6 6 ↔ 5 7 ↔ 4 8 ↔ 3 9 ↔ 2

NAD+ + Phenyl-lactic acid = NADH + Phenyl-pyruvic acid (links: NAD+ + Phenyl-lactic acid = NADH + 2-Oxo-3-phenylpropanoic acid)

NAD+ <Mapping> AtomMap:BMCCPUAPt031$BMCCPUAPt032$0 NADH 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32 Phenyl-lactic acid <Mapping> AtomMap:BMMCBZ1Sk046$BMMCBZ1Sj049$0 2-Oxo-3-phenylpropanoic acid 1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9