PKS:An14g04850
From Metabolomics.JP
| Polyketide Top | Species List | UniRef90 Class | UniRef50 Class | Gene Class | Domains (by CDD) |
Domains (by MAPSI) |
| Aspergillus niger CBS 513.88 (GenBank XP_001401108) all species | |||
|---|---|---|---|
| Class | NRPKS (length: 1869) all classes Class 02.NRPS-PKS(NFC) in KS domain phylogeny | Reliability | |
| Product | GeneName | ||
| UniProt,UniRef90 | - , - | UniRef50 | - |
| Domain by MAPSI | ACP-KS-AT-ACP | ||
| Domain by CDD | LuxE-PP-KS-AT-PP | ||
| Domain by ITER-DB | {{{ITERDB}}} | ||
| Estimated Domain | |||
| Description | hypothetical protein An14g04850 [Aspergillus niger] | ||
| Information | domain-AA-adenyl-dom and PP before KS . Title: strong similarity to pimaricin polyketide synthase pimS2 - Streptomyces natalensis; Catalytic activity: polyketide synthases are multifunctional enzymes-containing oxidoreductase-transferase and dehydratase activity; some of the typical domains present in polyketide synthases are recognized in the predicted ORF.; Function: pimS2 of S. natalensis is involved in the biosynthesis of the polyene macrolide pimaricin-important in the food industry as a preservative to prevent mould contamination of foods.; Pathway: polyketides are generated from acetate by a pathway similar to the fatty acid metabolism-where some reduction or dehydratation reactions can be suppressed at specific biosynthetic steps-resulting in a much wider range of products-constituting a large family of often biologically active secondary metabolites.; Similarity: the predicted ORF shows strong similarity to different fungal polyketide synthases.? | ||
| References | |||
| Link | AspGD | ||
This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)
