Enzyme:1.1.1.86

Revision as of 09:00, 2 February 2009

(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase(isomerizing)
Systematic Name	(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase(isomerizing)
Common Name	ketol-acid reductoisomerase dihydroxyisovalerate dehydrogenase (isomerizing) acetohydroxy acid isomeroreductase alpha-keto-beta-hydroxylacyl reductoisomerase 2-hydroxy-3-keto acid reductoisomerase

NADPH + (S)-2-Aceto-lactic acid => NADP+ + (R)-2,3-Dihydroxy-3-methyl-butanoic acid
(links: NADP+ + (2S) -2-Hydroxy-2-methyl-3-oxobutanoic acid = NADPH + (R) -2,3-Dihydroxy-3-methyl-butanoic acid)

NADP+	<Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0	NADPH
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32

(2S) -2-Hydroxy-2-methyl-3-oxobutanoic acid	<Mapping> AtomMap:BMFYB4CAp007$BMFYB4CAr002$0	(R) -2,3-Dihydroxy-3-methyl-butanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 4 4 ↔ 3 5 ↔ 5

NADPH + (S)-2-Aceto-2-hydroxy-butanoic acid => NADP+ + (R)-2,3-Dihydroxy-3-methyl-pentanoic acid
(links: NADP+ + (2S) -2-Ethyl-2-hydroxy-3-oxobutanoic acid = NADPH + (2R,3R) -2,3-Dihydroxy-3-methylpentanoic acid)

NADP+	<Mapping> AtomMap:BMCCPUAPt033$BMCCPUAPt034$0	NADPH
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 19 ↔ 19 20 ↔ 20 21 ↔ 21 22 ↔ 22 23 ↔ 23 24 ↔ 24 25 ↔ 25 26 ↔ 26 28 ↔ 28 29 ↔ 29 30 ↔ 30 31 ↔ 31 32 ↔ 32

(2S) -2-Ethyl-2-hydroxy-3-oxobutanoic acid	<Mapping> AtomMap:BMFYB4CAi006$BMFYB5CAr002$0	(2R,3R) -2,3-Dihydroxy-3-methylpentanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 4 4 ↔ 5 5 ↔ 3 6 ↔ 6

@@ Line 3: / Line 3: @@
 |SysName=(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase(isomerizing)
 |names=&&ketol-acid reductoisomerase&&dihydroxyisovalerate dehydrogenase (isomerizing)&&acetohydroxy acid isomeroreductase&&alpha-keto-beta-hydroxylacyl reductoisomerase&&2-hydroxy-3-keto acid reductoisomerase
+}}
+{{Enzyme/Reaction| reaction= NADPH + (S)-2-Aceto-lactic acid => NADP+ + (R)-2,3-Dihydroxy-3-methyl-butanoic acid
+| list=
+&& BMCCPUAPt033$BMCCPUAPt034$0
+&& BMFYB4CAp007$BMFYB4CAr002$0
+}}
+{{Enzyme/Reaction| reaction= NADPH + (S)-2-Aceto-2-hydroxy-butanoic acid => NADP+ + (R)-2,3-Dihydroxy-3-methyl-pentanoic acid
+| list=
+&& BMCCPUAPt033$BMCCPUAPt034$0
+&& BMFYB4CAi006$BMFYB5CAr002$0
 }}

IDs and Links
IUBMB	EC1
ExPaSy	NiceZyme 1.1.1.86