Enzyme:6.2.1.4

Revision as of 09:00, 2 February 2009

succinate:CoA ligase (GDP-forming)
Systematic Name	succinate:CoA ligase (GDP-forming)
Common Name	succinate-CoA ligase (GDP-forming) succinyl-CoA synthetase (GDP-forming) succinyl coenzyme A synthetase (guanosine diphosphate-forming) succinate thiokinase succinic thiokinase

CoA	<Mapping> AtomMap:BMCCPUAPf023$BMFYB4CAa019$0	4- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethylsulfanyl] -2-methylidene-4-oxobutanoic acid
	1 ↔ 9 2 ↔ 10 3 ↔ 11 4 ↔ 12 5 ↔ 13 6 ↔ 14 7 ↔ 15 8 ↔ 16 9 ↔ 17 10 ↔ 18 11 ↔ 19 12 ↔ 20 13 ↔ 21 14 ↔ 22 15 ↔ 23 32 ↔ 40 33 ↔ 41 34 ↔ 43 35 ↔ 42 36 ↔ 44 37 ↔ 45 38 ↔ 46 39 ↔ 47 40 ↔ 48 41 ↔ 49 42 ↔ 50 43 ↔ 51 44 ↔ 52 45 ↔ 53

ITP	<Mapping> AtomMap:BMCCPUXA0017$BMCCPUXA0013$0	IDP
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15

Itaconic acid	<Mapping> AtomMap:BMFYB4DAs018$BMFYB4CAa019$0	4- [2- [3- [ [4- [ [ [(2R,3S,4R,5R) -5- (6-Aminopurin-9-yl) -4-hydroxy-3-phosphonooxyoxolan-2-yl] methoxy-hydroxyphosphoryl] oxy-hydroxyphosphoryl] oxy-2-hydroxy-3,3-dimethylbutanoyl] amino] propanoylamino] ethylsulfanyl] -2-methylidene-4-oxobutanoic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5

CoA + GTP + Succinic acid = Succinyl-CoA + GDP + Orthophosphate
(links: Succinyl-CoA + GTP + Butanedioic acid = CoA + GDP + Succinyl-CoA)

Succinyl-CoA	<Mapping> AtomMap:BMFYS4CAa023$BMCCPUAPf023$0	CoA
	8 ↔ 1 9 ↔ 2 10 ↔ 3 11 ↔ 4 12 ↔ 5 13 ↔ 6 14 ↔ 7 15 ↔ 8 16 ↔ 9 17 ↔ 10 18 ↔ 11 19 ↔ 12 20 ↔ 13 21 ↔ 14 22 ↔ 15 39 ↔ 32 40 ↔ 33 41 ↔ 35 42 ↔ 34 43 ↔ 36 44 ↔ 37 45 ↔ 38 46 ↔ 39 47 ↔ 40 48 ↔ 41 49 ↔ 42 50 ↔ 43 51 ↔ 44 52 ↔ 45

GTP	<Mapping> AtomMap:BMCCPUGU0013$BMCCPUGU0011$0	GDP
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 10 ↔ 10 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15 16 ↔ 16

Butanedioic acid	<Mapping> AtomMap:BMFYS4DA0015$BMFYS4CAa023$1 (2nd)	Succinyl-CoA
	1 ↔ 4 2 ↔ 3 3 ↔ 2 4 ↔ 1

CoA + ITP + Succinic acid = Succinyl-CoA + IDP + Orthophosphate
(links: Succinyl-CoA + ITP + Butanedioic acid = CoA + IDP + Succinyl-CoA)

Succinyl-CoA	<Mapping> AtomMap:BMFYS4CAa023$BMCCPUAPf023$0	CoA
	8 ↔ 1 9 ↔ 2 10 ↔ 3 11 ↔ 4 12 ↔ 5 13 ↔ 6 14 ↔ 7 15 ↔ 8 16 ↔ 9 17 ↔ 10 18 ↔ 11 19 ↔ 12 20 ↔ 13 21 ↔ 14 22 ↔ 15 39 ↔ 32 40 ↔ 33 41 ↔ 35 42 ↔ 34 43 ↔ 36 44 ↔ 37 45 ↔ 38 46 ↔ 39 47 ↔ 40 48 ↔ 41 49 ↔ 42 50 ↔ 43 51 ↔ 44 52 ↔ 45

ITP	<Mapping> AtomMap:BMCCPUXA0017$BMCCPUXA0013$0	IDP
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 9 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 14 15 ↔ 15

Butanedioic acid	<Mapping> AtomMap:BMFYS4DA0015$BMFYS4CAa023$1 (2nd)	Succinyl-CoA
	1 ↔ 4 2 ↔ 3 3 ↔ 2 4 ↔ 1

@@ Line 3: / Line 3: @@
 |SysName=succinate:CoA ligase (GDP-forming)
 |names=&&succinate-CoA ligase (GDP-forming)&&succinyl-CoA synthetase (GDP-forming)&&succinyl coenzyme A synthetase (guanosine diphosphate-forming)&&succinate thiokinase&&succinic thiokinase
+}}
+{{Enzyme/Reaction| reaction= CoA + ITP + Itaconic acid = Itaconyl-CoA + IDP + Orthophosphate
+| list=
+&& BMCCPUAPf023$BMFYB4CAa019$0
+&& BMCCPUXA0017$BMCCPUXA0013$0
+&& BMFYB4DAs018$BMFYB4CAa019$0
+}}
+{{Enzyme/Reaction| reaction= CoA + GTP + Succinic acid = Succinyl-CoA + GDP + Orthophosphate
+| list=
+&& BMFYS4CAa023$BMCCPUAPf023$0
+&& BMCCPUGU0013$BMCCPUGU0011$0
+&& BMFYS4DA0015$BMFYS4CAa023$1
+}}
+{{Enzyme/Reaction| reaction= CoA + ITP + Succinic acid = Succinyl-CoA + IDP + Orthophosphate
+| list=
+&& BMFYS4CAa023$BMCCPUAPf023$0
+&& BMCCPUXA0017$BMCCPUXA0013$0
+&& BMFYS4DA0015$BMFYS4CAa023$1
 }}

IDs and Links
IUBMB	EC6
ExPaSy	NiceZyme 6.2.1.4