PKS:AN8209

Latest revision as of 15:39, 26 March 2013

Aspergillus nidulans FGSC A4 (GenBank CBF74114) all species
Class	NRPKS (length: 2157) all classes Class in KS domain phylogeny	Reliability	identified
Product	naphthopyrone	GeneName	wA
UniProt,UniRef90	C8V774 , Q03149	UniRef50	Q03149
Domain by MAPSI	KS-AT-ACP-ACP-CYC (notation help / all patterns)
Domain by CDD	(AT)-KS-AT-PP-PP-TE (notation help / all patterns)
Domain by ITER-DB	KS-AT-ACP-ACP-CYC (notation help / all patterns)
Estimated Domain	SAT-KS-AT-PT-ACP-ACP-TE/CLC
Description	TPA: Conidial yellow pigment biosynthesis polyketide synthase (PKS)(EC 2.3.1.-) [Source:UniProtKB/Swiss-Prot;Acc:Q03149] [Aspergillus nidulans FGSC A4]
Information	Similar with CAA46695. An additional and incomplete AT domain before KS domain.Predicted cluster size: 5 genes.
References	Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC: Illuminating the diversity of aromatic polyketide synthases in aspergillus nidulans. J Am Chem Soc, 2012 Andersen M R, Nielsen J B, Klitgaard A, Petersen L M, Zachariasen M, Hansen T J, Blicher L H, Gotfredsen C H, Larsen T O, Nielsen K F, Mortensen U H: Accurate prediction of secondary metabolite gene clusters in filamentous fungi. Proc Natl Acad Sci U S A 110(1): E99-107. 2013 Li Y, Image, II, Xu W, Image I, Tang Y: Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains. J Biol Chem 285(30):22764-22773, 2010
Link	AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)

@@ Line 11: / Line 11: @@
 |MAPSI=KS-AT-ACP-ACP-CYC
 |CDD=(AT)-KS-AT-PP-PP-TE
+|ITERDB=KS-AT-ACP-ACP-CYC
+|InferredDomain=SAT-KS-AT-PT-ACP-ACP-TE/CLC
 |class=NRPKS
 |reliability=identified
 |description=TPA: Conidial yellow pigment biosynthesis polyketide synthase (PKS)(EC 2.3.1.-) [Source:UniProtKB/Swiss-Prot;Acc:Q03149] [Aspergillus nidulans FGSC A4]
-|information=similar with ANid02. additional and incompleted AT before KS�BTPA: conidial pigment biosynthesis polyketide synthase (Eurofung); Comment: Helmstaedt: SP:Q03149: Conidial yellow pigment biosynthesis polyketide synthase (EC 2.3.1.-)(PKS). {Emericella nidulans;} GB|CAA46695.2|14715677|ANWA polyketide synthase for naphthopyrone YWA1 {Emericella nidulans;} PMID: 2227390-PMID: 2172077-PMID: 1465094-PMID: 1465094 identical to Aspergillus fumigatus pksP (PMID: 9832321)-localized in phialides/conidia and also hyphae when isolated from lung Pocsi-Miskei-Karanyi: Orthologue of A.fumigatus:Alb1 involved in response to oxidative stress-product name: Polyketide synthase ?
+|information=Similar with CAA46695. An additional and incomplete AT domain before KS domain.Predicted cluster size: 5 genes.
 |length=2157
-|references=\*Li.+2010$
+|references=\*Li.+2010$~\*Ahuja.+2012$~\*Andersen.+2013$
 }}
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