PKS:AN1034

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(update information (gene cluster) and reference)
 
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|species=Aspergillus nidulans FGSC A4
 
|species=Aspergillus nidulans FGSC A4
 
|taxonomy=Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Pezizomycotina; Leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; Emericella
 
|taxonomy=Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomyceta; Pezizomycotina; Leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; Emericella
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|product=
+
|product=asperfuranone
 
|GenBank=XP_658638
 
|GenBank=XP_658638
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|geneName=pks13
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|UniProt=C8VTX9
 +
|UniRef90=C8VTX9
 +
|UniRef50=C8VTX9
 +
|geneName=pks13(afoE)
 
|MAPSI=KS-AT-ACP
 
|MAPSI=KS-AT-ACP
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|CDD=KS-AT-PP-ME-KR
+
|CDD=KS-AT-PP-ME-TE
 +
|ITERDB=KS-AT-ACP
 +
|InferredDomain=SAT-KS-AT-PT-ACP-ME-R
 
|class=NRPKS
 
|class=NRPKS
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|reliability=
+
|reliability=verified
 
|description=hypothetical protein AN1034.2 [Aspergillus nidulans FGSC A4]
 
|description=hypothetical protein AN1034.2 [Aspergillus nidulans FGSC A4]
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|information=
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|information=Putative polyketide synthase; required for asperfuranone biosynthesis; transcriptionally induced by scrP overexpression.
 
|length=2793
 
|length=2793
 +
|references=\*Fisch.+2009$~\*Ahuja.+2012$~\*Chiang.+2009$~\*Andersen.+2013$
 
}}
 
}}
 
{{{{NAMESPACE}}/Footer}}
 
{{{{NAMESPACE}}/Footer}}

Latest revision as of 13:00, 28 March 2013

Polyketide Top Species List UniRef90 Class UniRef50 Class Gene Class Domains
(by CDD) 		Domains
(by MAPSI)
Aspergillus nidulans FGSC A4 (GenBank XP_658638) all species
Class NRPKS (length: 2793) all classes   Class in KS domain phylogeny Reliability verified
Product asperfuranone GeneName pks13(afoE)
UniProt,UniRef90 C8VTX9 , C8VTX9 UniRef50 C8VTX9
Domain by MAPSI KS-AT-ACP

(notation help / all patterns)

Domain by CDD KS-AT-PP-ME-TE

(notation help / all patterns)

Domain by ITER-DB KS-AT-ACP

(notation help / all patterns)

Estimated Domain SAT-KS-AT-PT-ACP-ME-R
Description hypothetical protein AN1034.2 [Aspergillus nidulans FGSC A4]
Information Putative polyketide synthase; required for asperfuranone biosynthesis; transcriptionally induced by scrP overexpression.
References
  • Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC: Illuminating the diversity of aromatic polyketide synthases in aspergillus nidulans. J Am Chem Soc, 2012
  • Andersen M R, Nielsen J B, Klitgaard A, Petersen L M, Zachariasen M, Hansen T J, Blicher L H, Gotfredsen C H, Larsen T O, Nielsen K F, Mortensen U H: Accurate prediction of secondary metabolite gene clusters in filamentous fungi. Proc Natl Acad Sci U S A 110(1): E99-107. 2013
  • Chiang YM, Szewczyk E, Davidson AD, Keller N, Oakley BR, Wang CC: A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in aspergillus nidulans. J Am Chem Soc 131(8):2965-2970, 2009
  • Fisch KM, Gillaspy AF, Gipson M, Henrikson JC, Hoover AR, Jackson L, Najar FZ, Wagele H, Cichewicz RH: Chemical induction of silent biosynthetic pathway transcription in aspergillus niger. J Ind Microbiol Biotechnol 36(9):1199-1213, 2009
Link AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)

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