PKS:An15g04140

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Revision as of 09:00, 18 December 2010

Polyketide Top Species List UniRef90 Class UniRef50 Class Gene Class Domains
(by CDD)
Domains
(by MAPSI)
Aspergillus niger CBS 513.88 (GenBank XP_001396949) all species
Class RPKS (length: 2565) all classes   Class 39.R-PKS_VI in KS domain phylogeny Reliability
Product GeneName
UniProt,UniRef90 [1] , [2] UniRef50 [3]
Domain by MAPSI KS-AT-DH-ER-KR-ACP

(notation help / all patterns)

Domain by CDD KS-AT-DH-ME-ER-KR-PP

(notation help / all patterns)

Domain by ITER-DB {{{ITERDB}}}

(notation help / all patterns)

Estimated Domain
Description hypothetical protein An15g04140 [Aspergillus niger]
Information Title: strong similarity to polyketide synthase PKS1 - Cochliobolus heterostrophus; Function: PKS1 from C. heterostrophus encodes a multifunctional polyketide synthase with six catalytic domains: beta-ketoacyl synthase-acyltransferase-dehydratase-enoyl reductase-beta-ketoacyl reductase and acyl carrier protein.; Phenotype: PKS1 in race T of the fungal pathogen C. heterostrophus was inactivated by targeted gene disruption-T-toxin production and high virulence were eliminated-indicating that this PKS is required for fungal virulence.; Remark: race T of the fungal pathogen C. heterostrophus may have acquired PKS1 by horizontal DNA-transfer rather than by vertical inheritance from an ancestral strain.; (1.3.1.9); (2.3.1.-)?
References
Link AspGD

This work is performed by ShuHsi Lin (TW), Toshitaka Kumagai and Masanori Arita (JP)

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