Enzyme:2.1.2.1

Revision as of 09:00, 2 February 2009

5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Systematic Name	5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Common Name	glycine hydroxymethyltransferase serine aldolase threonine aldolase serine hydroxymethylase serine hydroxymethyltransferase

(2R,3S) -2-Amino-3-hydroxybutanoic acid	<Mapping> AtomMap:BMAAS4HO0004$BMAAS2AK0001$0	2-Amino-acetic acid
	1 ↔ 1 2 ↔ 2 5 ↔ 3

(2R,3S) -2-Amino-3-hydroxybutanoic acid	<Mapping> AtomMap:BMAAS4HO0004$BMFYS2AL0001$0	Acetaldehyde
	3 ↔ 1 4 ↔ 2

[(5S) -5-Amino-4,6-dihydroxy-6-oxohexyl] -trimethylazanium	<Mapping> AtomMap:BMAXS6ANq001$BMFYB4ALb004$0	4-Trimethyl-ammonio-butanal
	3 ↔ 1 4 ↔ 2 5 ↔ 3 6 ↔ 4 8 ↔ 5 9 ↔ 8 10 ↔ 7 11 ↔ 6

[(5S) -5-Amino-4,6-dihydroxy-6-oxohexyl] -trimethylazanium	<Mapping> AtomMap:BMAXS6ANq001$BMAAS2AK0001$0	2-Amino-acetic acid
	1 ↔ 1 2 ↔ 2 7 ↔ 3

L-Tetrahydro-folic acid	<Mapping> AtomMap:BMCCPTFO0013$BMCCPTFOs005$0	5,10-Methylene-tetrahydro-folic acid
	1 ↔ 1 2 ↔ 2 3 ↔ 3 4 ↔ 4 5 ↔ 5 6 ↔ 6 7 ↔ 7 8 ↔ 8 9 ↔ 14 10 ↔ 10 11 ↔ 11 12 ↔ 12 13 ↔ 13 14 ↔ 15 15 ↔ 20 16 ↔ 19 17 ↔ 18 18 ↔ 17 19 ↔ 16 20 ↔ 21 21 ↔ 22 22 ↔ 23 23 ↔ 24 24 ↔ 25 25 ↔ 26 26 ↔ 27

(2S) -2-Amino-3-hydroxypropanoic acid	<Mapping> AtomMap:BMAAS3HO0002$BMAAS2AK0001$0	2-Amino-acetic acid
	1 ↔ 1 2 ↔ 2 4 ↔ 3

(2S) -2-Amino-3-hydroxypropanoic acid	<Mapping> AtomMap:BMAAS3HO0002$BMCCPTFOs005$0	5,10-Methylene-tetrahydro-folic acid
	3 ↔ 9

@@ Line 3: / Line 3: @@
 |SysName=5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
 |names=&&glycine hydroxymethyltransferase&&serine aldolase&&threonine aldolase&&serine hydroxymethylase&&serine hydroxymethyltransferase
+}}
+{{Enzyme/Reaction| reaction= L-Threonine = Glycine + Acetaldehyde
+| list=
+&& BMAAS4HO0004$BMAAS2AK0001$0
+&& BMAAS4HO0004$BMFYS2AL0001$0
+}}
+{{Enzyme/Reaction| reaction= 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine = 4-Trimethyl-ammonio-butanal + Glycine
+| list=
+&& BMAXS6ANq001$BMFYB4ALb004$0
+&& BMAXS6ANq001$BMAAS2AK0001$0
+}}
+{{Enzyme/Reaction| reaction= L-Tetrahydro-folic acid + L-Serine = 5,10-Methylene-tetrahydro-folic acid + Glycine + H2O
+| list=
+&& BMCCPTFO0013$BMCCPTFOs005$0
+&& BMAAS3HO0002$BMAAS2AK0001$0
+&& BMAAS3HO0002$BMCCPTFOs005$0
 }}

IDs and Links
IUBMB	EC2
ExPaSy	NiceZyme 2.1.2.1