Category:BMAA

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==Class Overview==
 
==Class Overview==
 
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An amino acid has a carbon connected by an amino group and a carboxyl group (called an alpha carbon).  Proteins are constituted from 20 amino acids.   
 
An amino acid has a carbon connected by an amino group and a carboxyl group (called an alpha carbon).  Proteins are constituted from 20 amino acids.   
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たんぱく質を構成するアミノ酸は20種類あります。いずれもアミノ基、カルボキシル基、水素が結合した炭素(α炭素)を持ち、残りの結合手が異なる構造になっています。
 
たんぱく質を構成するアミノ酸は20種類あります。いずれもアミノ基、カルボキシル基、水素が結合した炭素(α炭素)を持ち、残りの結合手が異なる構造になっています。
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== Physicochemical Characters ==
 
== Physicochemical Characters ==
 +
{{Doc:Metabolite/Amino Acid/Table}}
  
{| class="collapsible" border="1" cellspacing="0"
 
! colspan = 7 | Character of amino acids
 
|-
 
| ID || Code || Symbol || Structure || Character || pI || Required for human?
 
|-
 
| [[{{GetMetaboliteID|L-Alanine||BMAA}}]] || Ala || A || -CH<sub>3</sub> || neutral || 6.0 ||
 
|-
 
| [[{{GetMetaboliteID|L-Serine||BMAA}}]] || Ser || S || -CH<sub>2</sub>OH || neutral || 5.7 || 
 
|-
 
| [[{{GetMetaboliteID|L-Threonine||BMAA}}]] || Thr || T || -CH(OH)CH<sub>3</sub> || neutral || 5.6 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Valine||BMAA}}]] || Val || V || -CH(CH<sub>3</sub>)<sub>2</sub> || neutral, branched || 6.0 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Leucine||BMAA}}]] || Leu || L || -CH<sub>2</sub>CH(CH<sub>3</sub>)<sub>2</sub> || neutral, branched || 6.0 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Isoleucine||BMAA}}]] || Ile || I || -CH(CH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub> || neutral, branched || 6.0 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Aspartate||BMAA}}]] || Asp || D || -CH<sub>2</sub>COOH || acidic || 2.8 ||
 
|-
 
| [[{{GetMetaboliteID|L-Glutamate||BMAA}}]] || Glu || E || -CH<sub>2</sub>CH<sub>2</sub>COOH || acidic || 3.2 ||
 
|-
 
| [[{{GetMetaboliteID|L-Asparagine||BMAA}}]] || Asn || N || -CH<sub>2</sub>CONH<sub>2</sub> || acidic, amido || 5.4 ||
 
|-
 
| [[{{GetMetaboliteID|L-Glutamine||BMAA}}]] || Gln || Q || -CH<sub>2</sub>CH<sub>2</sub>CONH<sub>2</sub> || acidic, amido || 5.7 ||
 
|-
 
| [[{{GetMetaboliteID|L-Lysine||BMAA}}]] || Lys || K || -(CH<sub>2</sub>)<sub>4</sub>NH<sub>3</sub> || basic || 9.7 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Arginine||BMAA}}]] || Arg || R || -(CH<sub>2</sub>)<sub>3</sub>NHC(=NH)NH<sub>2</sub> || basic || 10.8 ||
 
|-
 
| [[{{GetMetaboliteID|L-Cysteine||BMAA}}]] || Cys || C || -CH<sub>2</sub>SH || neutral, S || 5.1 ||
 
|-
 
| [[{{GetMetaboliteID|L-Methionine||BMAA}}]] || Met || M || -(CH<sub>2</sub>)<sub>2</sub>SCH<sub>3</sub> || neutral, S || 5.7 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Phenylalanine||BMAA}}]] || Phe || F || -CH<sub>2</sub>-Benz || neutral, aromatic || 5.5 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Tyrosine||BMAA}}]] || Tyr || Y || -CH<sub>2</sub>-Benz-OH || neutral, aromatic || 5.7 ||
 
|-
 
| [[{{GetMetaboliteID|L-Tryptophan||BMAA}}]] || Trp || W || -CH<sub>2</sub>-Indole || neutral, aromatic || 5.9 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Histidine||BMAA}}]] || His || H || -CH<sub>2</sub>-Imidazole || basic, atomatic || 7.6 || yes
 
|-
 
| [[{{GetMetaboliteID|L-Proline||BMAA}}]] || Pro || P || -NH-(CH<sub>2</sub>)<sub>3</sub>- || neutral, cyclic, 2nd amine || 6.2 ||
 
|}
 
 
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==D and L in Amino Acid==
 
==D and L in Amino Acid==
 
===Definition===
 
===Definition===

Revision as of 12:12, 1 June 2011

Amino Acids


Basic Metabolism Top
(代謝トップ)
Molecule Index
(化合物索引)
EC classes
( EC分類)
Input New Data
(新規入力)

Upper classes : BM Basic Metabolites

Contents

Class Overview

An amino acid has a carbon connected by an amino group and a carboxyl group (called an alpha carbon). Proteins are constituted from 20 amino acids.

Straight Class
 BMAAS2 (1 pages) Straight length 2
Gly
BMAAS2.png
 BMAAS3 (19 pages) Straight length 3
Ser, Cys, Ala
BMAAS3.png
 BMAAS4 (16 pages) Straight length 4
Asp, Asn, Thr
BMAAS4.png
 BMAAS5 (16 pages) Straight length 5
Gln, Glu
BMAAS5.png
 BMAAS6 (6 pages) Straight length 6
Lys
BMAAS6.png
Branched Class
 BMAAB4 (2 pages) Branched length 4
Val, Met
BMAAB4.png
 BMAAB5 (3 pages) Branched length 5
Arg, Leu, Ile
BMAAB5.png
 BMAAB6 (0 pages) Branched length 6
BMAAB6.png
Cyclic Class (click here to visit another page)

Physicochemical Characters

Doc:Metabolite/Amino Acid/Table

D and L in Amino Acid

Definition

Except for glycine, an amino acid contains a chiral carbon, distinguished by D or L (R or S). In the Fischer projection, which places the carboxyl group upward and amino acid-specific side-chain downward, the amino group must comes either left or right, protruding from the paper plane. If the hydrogen is left and amino group is right, the amino acid is called D, after D-glyceraldehide. If the amino group is left, it is called L.

D-glyceraldehyde.gif D-serine.gif L-serine.gif

DL and RS do not coincide

In the Cahn-Ingold-Prelog (or RS) notation, 19 L-amino acids become S-form (when H is placed behind the paper plane, the amino group, carboxyl group and side chain are arranged anticlockwise). Only L-cysteine becomes R-form because S in its side chain makes the arrangement in the different order: amino group, side chain, and carboxyl group. For this reason, although its tetrahedal configuration is the same as the rest of amino acids, it is R-form. Likewise, cystine is R-form too.

Glycine has no chiral carbon

Glycine has two Hydrogen branches and therefore not chiral. The amino group of proline is included in the ring sturucture and therefore secondary amine.

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