Doc:Ginkgo

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イチョウ葉の抽出液はフラボノイドやテルペノイドを多量に含み、認知症の予防・改善効果が報告されてきた。
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しかし8年にわたる大規模な臨床試験の結果、高齢者の認知症やアルツハイマー症には予防・改善効果が無く<ref>DeKosky ST, Williamson JD, Fitzpatrick AL, Kronmal RA, Ives DG, Saxton JA, Lopez OL, Burke G, Carlson MC, Fried LP, Kuller LH, Robbins JA, Tracy RP, Woolard NF, Dunn L, Snitz BE, Nahin RL, Furberg CD; Ginkgo Evaluation of Memory (GEM) Study Investigators (2008) Ginkgo biloba for prevention of dementia: a randomized controlled trial ''JAMA'' 300(19):2253-2262</ref>、ボケの防止にも効果が無い<ref>Snitz BE, O'Meara ES, Carlson MC, Arnold AM, Ives DG, Rapp SR, Saxton J, Lopez OL, Dunn LO, Sink KM, DeKosky ST; Ginkgo Evaluation of Memory (GEM) Study Investigators (2009) Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial ''JAMA'' 302(24):2663-2670</ref>ことがわかっている。
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The extract of [[Species:Ginkgo|''Ginkgo biloba'']] contains various flavonoids and terpenoids, and many groups reported its beneficial effects on dementia and other memory-related impairments. After 8 years of extensive epidemiologic study, however, Ginkgo extract improved neither all-cause dementia, Alzheimer disease<ref name="AD">DeKosky ST, Williamson JD, Fitzpatrick AL, Kronmal RA, Ives DG, Saxton JA, Lopez OL, Burke G, Carlson MC, Fried LP, Kuller LH, Robbins JA, Tracy RP, Woolard NF, Dunn L, Snitz BE, Nahin RL, Furberg CD; Ginkgo Evaluation of Memory (GEM) Study Investigators (2008) Ginkgo biloba for prevention of dementia: a randomized controlled trial ''JAMA'' 300(19):2253-2262</ref>, nor long-term cognitive functions<ref name="mem">Snitz BE, O'Meara ES, Carlson MC, Arnold AM, Ives DG, Rapp SR, Saxton J, Lopez OL, Dunn LO, Sink KM, DeKosky ST; Ginkgo Evaluation of Memory (GEM) Study Investigators (2009) Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial ''JAMA'' 302(24):2663-2670</ref>.
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|[[Species:Ginkgo|イチョウ葉]]の抽出液はフラボノイドやテルペノイドを多量に含み、認知症の予防・改善効果が報告されてきた。
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しかし8年にわたる大規模な臨床試験の結果、高齢者の認知症やアルツハイマー症には予防・改善効果が無く<ref name="AD"/>、ボケの防止にも効果が無い<ref name="mem"/>ことがわかっている。
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'''References:'''
References:
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Revision as of 14:52, 24 February 2010

The extract of Ginkgo biloba contains various flavonoids and terpenoids, and many groups reported its beneficial effects on dementia and other memory-related impairments. After 8 years of extensive epidemiologic study, however, Ginkgo extract improved neither all-cause dementia, Alzheimer disease[1], nor long-term cognitive functions[2].

References:

  1. DeKosky ST, Williamson JD, Fitzpatrick AL, Kronmal RA, Ives DG, Saxton JA, Lopez OL, Burke G, Carlson MC, Fried LP, Kuller LH, Robbins JA, Tracy RP, Woolard NF, Dunn L, Snitz BE, Nahin RL, Furberg CD; Ginkgo Evaluation of Memory (GEM) Study Investigators (2008) Ginkgo biloba for prevention of dementia: a randomized controlled trial JAMA 300(19):2253-2262
  2. Snitz BE, O'Meara ES, Carlson MC, Arnold AM, Ives DG, Rapp SR, Saxton J, Lopez OL, Dunn LO, Sink KM, DeKosky ST; Ginkgo Evaluation of Memory (GEM) Study Investigators (2009) Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial JAMA 302(24):2663-2670
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