Doc:Antioxidant - Revision history

Adm at 02:03, 1 October 2010

2010-10-01T02:03:13Z

Adm at 02:02, 1 October 2010

2010-10-01T02:02:09Z

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2010-10-01T01:59:38Z

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2010-10-01T01:39:24Z

‎{{Bilingual|食べた場合|In vivo study}}

Adm: /* {{Bilingual|食べた場合|In vivo study}} */

2010-10-01T01:39:09Z

‎{{Bilingual|食べた場合|In vivo study}}

Adm: /* {{Bilingual|食べた場合|In vivo study}} */

2010-10-01T01:36:56Z

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2010-10-01T01:30:45Z

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Adm at 10:57, 30 September 2010

2010-09-30T10:57:49Z

Adm at 07:59, 30 September 2010

2010-09-30T07:59:10Z

Adm at 06:19, 30 September 2010

2010-09-30T06:19:03Z

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 <references/>
+=={{Bilingual|抗酸化能一覧|Table for antioxidant activities}}==
 {| class="wikitable"
 ! colspan="3"| Relative total antioxidant activities<ref>Rice-Evans C, Miller N, Paganga G (1997) "Antioxidant properties of phenolic compounds" ''Trends Plant Sci'' 2(4):152-159</ref>

@@ Line 38: / Line 38: @@
 ==={{Bilingual|食べた場合|In vivo study}}===
 {{Twocolumn|
-Although antioxidant activities of flavonoids are several times higher than vitamin C or E in vitro, their plasma and intracellular concentration after intake is 100-1000 times lower than vitamin C or uric acid. The antioxidant function in vivo is therefore considered negligible<ref>Lotito SB, Frei B (2006) "Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?" ''Free Radic Biol Med'' 41(12):1727-1746 PMID 17157175</ref>.
+Although antioxidant activities of flavonoids are several times higher than vitamin C or E in vitro, their plasma and intracellular concentration after intake is over 100 times lower than vitamin C or uric acid. The antioxidant function in vivo is therefore considered negligible<ref>Lotito SB, Frei B (2006) "Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?" ''Free Radic Biol Med'' 41(12):1727-1746 PMID 17157175</ref>.
+|
-試験管内ではフラボノイドの抗酸化能はビタミンCやEの数倍あるのですが、摂取後の血中濃度はビタミンCや尿酸の100から1000倍も低くなります。そのため、体内における抗酸化作用は殆ど無いと考えられます。
+試験管内ではフラボノイドの抗酸化能はビタミンCやEの数倍あるのですが、摂取後の血中濃度はビタミンCや尿酸の100倍以上も低くなります。そのため、体内における抗酸化作用は殆ど無いと考えられます。
 }}
@@ Line 55: / Line 55: @@
 <ref>Maxwell SR, Thomason H, Sandler D, Leguen C, Baxter MA, Thorpe GH, Jones AF, Barnett AH (1997) "Antioxidant status in patients with uncomplicated insulin-dependent and non-insulin-dependent diabetes mellitus" ''Eur J Clin Invest'' 27(6):484-490 PMID 9229228</ref>
 |-
-| vitamin E || 8-28 &mu;mol/L  || <ref>Farrell PM (1980) Vitamin E: a comprehensive treaties (Machlin LJ ed.) pp.520-620, Marcel Dekker, New York</ref>
+| vitamin E || 8-28 &mu;mol/L  ||
 |-
 | flavonoids || < 10 &mu;mol/L for flavanones<br/> < 1 &mu;mol/L for anthocyanins ||

@@ Line 42: / Line 42: @@
 試験管内ではフラボノイドの抗酸化能はビタミンCやEの数倍あるのですが、摂取後の血中濃度はビタミンCや尿酸の100から1000倍も低くなります。そのため、体内における抗酸化作用は殆ど無いと考えられます。
 }}
 <references/>

@@ Line 38: / Line 38: @@
 ==={{Bilingual|食べた場合|In vivo study}}===
 {{Twocolumn|
-Although antioxidant activities of flavonoids are several times higher than vitamin C or E in vitro, their plasma and intracellular concentration after intake is 100-1000 times lower than vitamin C or uric acid. The antioxidant function in vivo is therefore considered negligible<ref>Lotito SB, Frei B (2006) "Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?" ''Free Radic Biol Med'' 41(12):1727-1746 (PMID 17157175)</ref>.
+Although antioxidant activities of flavonoids are several times higher than vitamin C or E in vitro, their plasma and intracellular concentration after intake is 100-1000 times lower than vitamin C or uric acid. The antioxidant function in vivo is therefore considered negligible<ref>Lotito SB, Frei B (2006) "Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?" ''Free Radic Biol Med'' 41(12):1727-1746 PMID 17157175</ref>.
+|
 試験管内ではフラボノイドの抗酸化能はビタミンCやEの数倍あるのですが、摂取後の血中濃度はビタミンCや尿酸の100から1000倍も低くなります。そのため、体内における抗酸化作用は殆ど無いと考えられます。

@@ Line 38: / Line 38: @@
 ==={{Bilingual|食べた場合|In vivo study}}===
 {{Twocolumn|
-Although antioxidant activities of flavonoids are several times higher than vitamin C or E in vitro, their plasma and intracellular concentration after intake is 100-1000 times lower than vitamin C or uric acid. The antioxidant function in vivo is therefore considered negligible<ref>Frei B, Higdon JV (2003) "Antioxidant activity of tea polyphenols in vivo: evidence from animal studies" ''J Nutr'' 133(10):3275S-3284S</ref>.
+Although antioxidant activities of flavonoids are several times higher than vitamin C or E in vitro, their plasma and intracellular concentration after intake is 100-1000 times lower than vitamin C or uric acid. The antioxidant function in vivo is therefore considered negligible<ref>Lotito SB, Frei B (2006) "Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?" ''Free Radic Biol Med'' 41(12):1727-1746 (PMID 17157175)</ref>.
+|
 試験管内ではフラボノイドの抗酸化能はビタミンCやEの数倍あるのですが、摂取後の血中濃度はビタミンCや尿酸の100から1000倍も低くなります。そのため、体内における抗酸化作用は殆ど無いと考えられます。

← Older revision		Revision as of 01:30, 1 October 2010
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	試験管内ではフラボノイドの抗酸化能はビタミンCやEの数倍あるのですが、摂取後の血中濃度はビタミンCの100から1000倍も低くなります。そのため、体内における抗酸化作用は殆ど無いと考えられます。		試験管内ではフラボノイドの抗酸化能はビタミンCやEの数倍あるのですが、摂取後の血中濃度はビタミンCの100から1000倍も低くなります。そのため、体内における抗酸化作用は殆ど無いと考えられます。
	}}		}}
		+
		+	<references/>

@@ Line 1: / Line 1: @@
 {{Flavonoid/Header}}
 =={{Bilingual|フラボノイドの抗酸化能|Antioxidant Activity of Flavonoid}}==
 {{Twocolumn|
 The reactivity of an antioxidant is determined by its reactivity as a hydrogen or electron-donating agent, the fate of the resulting radical (unpaired electron), its reactivity with other antioxidant, and its metal-chelating potential.
@@ Line 33: / Line 35: @@
 }}
 <references/>
 {| class="wikitable"

@@ Line 35: / Line 35: @@
 {| class="wikitable"
-! colspan="3"| Relative total antioxidant activities
+! colspan="3"| Relative total antioxidant activities<ref>Rice-Evans C, Miller N, Paganga G (1997) "Antioxidant properties of phenolic compounds" ''Trends Plant Sci'' 2(4):152-159</ref>
 |-
 ! Antioxidant || Sources || Activity<sup>*</sup> (mM)
@@ Line 113: / Line 113: @@
 | colspan="3" style="text-align:left"| * ... Measured as the Trolox equivalent antioxidant activity (TEAC) - the concentration of Trolox with the equivalent antioxidant activity of a 1 mM concentration of the experimental substance
 |}

@@ Line 5: / Line 5: @@
 The reactivity can be assessed by applying the chromogenic redox indicator [http://en.wikipedia.org/wiki/ABTS ABTS<sup>+</sup>](radical cation of 2,2'-azino-bis (3-ethylbenzthiazoline 6-sulphonic acid) relative to [http://en.wikipedia.org/wiki/Trolox Trolox] (water-soluble vitamin E analogue).
+|
-抗酸化成分の反応性は、水素や電子を供与するドナーとしての性質、生じるラジカル（孤立電子）の行方、他の抗酸化成分との関係、金属をキレートするポテンシャルに左右される。
+抗酸化成分の反応性は、水素や電子を供与するドナーとしての性質、生じるラジカル（孤立電子）の行方、他の抗酸化成分との関係、金属をキレートするポテンシャルに左右されます。
-この反応性は発色性の酸化還元指標であるABTSを水溶性のビタミンE様物質Troloxと比較して測ることができる。
+この反応性は発色性の酸化還元指標であるABTSを水溶性のビタミンE様物質Troloxと比較して測ります。
 }}
 {| class="wikitable"
@@ Line 88: / Line 113: @@
 | colspan="3" style="text-align:left"| * ... Measured as the Trolox equivalent antioxidant activity (TEAC) - the concentration of Trolox with the equivalent antioxidant activity of a 1 mM concentration of the experimental substance
 |}