Category:BMAA - Revision history

Adm at 03:50, 2 June 2011

2011-06-02T03:50:05Z

Adm: /* D and L in Amino Acid */

2011-06-01T03:16:13Z

‎D and L in Amino Acid

Adm at 03:12, 1 June 2011

2011-06-01T03:12:47Z

Editor at 03:04, 23 October 2008

2008-10-23T03:04:07Z

Editor at 19:03, 4 September 2008

2008-09-04T19:03:16Z

Editor at 19:02, 4 September 2008

2008-09-04T19:02:02Z

Editor at 16:58, 4 September 2008

2008-09-04T16:58:48Z

Editor at 16:58, 4 September 2008

2008-09-04T16:58:01Z

Editor at 16:49, 4 September 2008

2008-09-04T16:49:16Z

Editor at 14:53, 4 September 2008

2008-09-04T14:53:18Z

@@ Line 40: / Line 40: @@
 == Physicochemical Characters ==
-{{Doc:Metabolite/Amino Acid/Table}}
+{{Aritalab:Lecture/Biochem/Amino Acid/Table}}
 ==D and L in Amino Acid==
-{{Doc:Metabolite/Amino Acid/DL}}
+{{Aritalab:Lecture/Biochem/Amino Acid/DL}}

@@ Line 43: / Line 43: @@
 ==D and L in Amino Acid==
-===Definition===
+{{Doc:Metabolite/Amino Acid/DL}}
-{{Twocolumn|
-Except for glycine, an amino acid contains a chiral carbon, distinguished by D or L (R or S).  In the Fischer projection, which places the carboxyl group upward and amino acid-specific side-chain downward, the amino group must comes either left or right, protruding from the paper plane.  If the hydrogen is left and amino group is right, the amino acid is called D, after D-glyceraldehide.  If the amino group is left, it is called L.
-−
-Glycineを除いて全てのアミノ酸は不斉炭素を持ち、D,L (R,S)の区別があります。カルボキシル基を上に、アミノ酸毎に異なる側鎖を下にしたFischer投影式を描くと、（紙面より上向きに配置される）アミノ基が左と右の場合があります。このうち水素が左アミノ基が右になるほうをD-グリセルアルデヒドに倣ってD-アミノ酸、アミノ基が左にくるものをL-アミノ酸とします。D-グリセルアルデヒドとセリンを並べてみると、ＤとＬの理由がよくわかります。
-}}
-<center>
-{|
-| [[Image:D-glyceraldehyde.gif]]
-| [[Image:D-serine.gif]]
-| [[Image:L-serine.gif]]
-|}
-</center>
-−
-===DL and RS do not coincide===
-{{Twocolumn|
-In the Cahn-Ingold-Prelog (or RS) notation, 19 L-amino acids become S-form (when H is placed behind the paper plane, the amino group, carboxyl group and side chain are arranged anticlockwise).  Only L-cysteine becomes R-form because S in its side chain makes the arrangement in the different order: amino group, side chain, and carboxyl group.  For this reason, although its tetrahedal configuration is the same as the rest of amino acids, it is R-form.  Likewise, cystine is R-form too.
-−
-アミノ酸をCahn-Ingold-Prelog則(RS)により表記してみると、１９のＬ-アミノ酸がS体となります（Ｈを紙面の裏側に配置したとき、アミノ基、カルボキシル基、側鎖の順にまわると左回りになる）。ただひとつL-cysteineは、側鎖にSがくるためにアミノ基、側鎖、カルボキシル基の順番に回ります。そのため正四面体構造における配置は一緒なのですが、R体となります。システインのほかにシスチンも同様の理由でR体となります。
-}}
-===Glycine has no chiral carbon===
-{{Twocolumn|
-Glycine has two Hydrogen branches and therefore not chiral.  The amino group of proline is included in the ring sturucture and therefore secondary amine.
-−
-Glycineは側鎖にＨを２つもつため、不斉炭素になりません。また、prolineはアミノ基が環構造の中に入っており、２級アミンとなります。}}

@@ Line 5: / Line 5: @@
 ==Class Overview==
 {{Twocolumn|
 An amino acid has a carbon connected by an amino group and a carboxyl group (called an alpha carbon).  Proteins are constituted from 20 amino acids.
-</p>|<p>
 たんぱく質を構成するアミノ酸は20種類あります。いずれもアミノ基、カルボキシル基、水素が結合した炭素（α炭素）を持ち、残りの結合手が異なる構造になっています。
 }}
@@ Line 42: / Line 40: @@
 == Physicochemical Characters ==
 ==D and L in Amino Acid==
 ===Definition===

@@ Line 17: / Line 17: @@
   |-
   |{{MapLink|FunctionalGroupBM|BMAAS2}}
-  |style="text-align:center"|Straight length 2<br>Gly<br>[[Image:BMAAS2.png|90px]]
+  |style="text-align:center"|Straight length 2<br>[[{{GetMetaboliteID|Glycine||BMAA}}|Gly]]<br>[[Image:BMAAS2.png|90px]]
   |{{MapLink|FunctionalGroupBM|BMAAS3}}
-  |style="text-align:center"|Straight length 3<br>Ser, Cys, [[BMAAS3AK0003|Ala]]<br>[[Image:BMAAS3.png|90px]]
+  |style="text-align:center"|Straight length 3<br>[[{{GetMetaboliteID|L-Serine||BMAA}}|Ser]], [[{{GetMetaboliteID|L-Cysteine||BMAA}}|Cys]], [[{{GetMetaboliteID|L-Alanine||BMAA}}|Ala]]<br>[[Image:BMAAS3.png|90px]]
   |{{MapLink|FunctionalGroupBM|BMAAS4}}
-  |style="text-align:center"|{{SearchLink/Main|Straight length 4}}<br>Asp, Asn, Thr<br>[[Image:BMAAS4.png|90px]]
+  |style="text-align:center"|Straight length 4<br>[[{{GetMetaboliteID|L-Aspartate||BMAA}}|Asp]], [[{{GetMetaboliteID|L-Asparagine||BMAA}}|Asn]], [[{{GetMetaboliteID|L-Threonine||BMAA}}|Thr]]<br>[[Image:BMAAS4.png|90px]]
   |-
   |{{MapLink|FunctionalGroupBM|BMAAS5}}
-  |style="text-align:center"|Straight length 5<br>Gln, Glu<br>[[Image:BMAAS5.png|90px]]
+  |style="text-align:center"|Straight length 5<br>[[{{GetMetaboliteID|L-Glutamine||BMAA}}|Gln]], [[{{GetMetaboliteID|L-Glutamate||BMAA}}|Glu]]<br>[[Image:BMAAS5.png|90px]]
   |{{MapLink|FunctionalGroupBM|BMAAS6}}
-  |style="text-align:center"|Straight length 6<br>Lys<br>[[Image:BMAAS6.png|90px]]
+  |style="text-align:center"|Straight length 6<br>[[{{GetMetaboliteID|L-Lysine||BMAA}}|Lys]]<br>[[Image:BMAAS6.png|90px]]
   | ||
   |-
@@ Line 32: / Line 32: @@
   |-
   |{{MapLink|FunctionalGroupBM|BMAAB4}}
-  |style="text-align:center"|Branched length 4<br>Val, Met<br>[[Image:BMAAB4.png|90px]]
+  |style="text-align:center"|Branched length 4<br>[[{{GetMetaboliteID|L-Valine||BMAA}}|Val]], [[{{GetMetaboliteID|L-Methionine||BMAA}}|Met]]<br>[[Image:BMAAB4.png|90px]]
   |{{MapLink|FunctionalGroupBM|BMAAB5}}
-  |style="text-align:center"|{{SearchLink/Main|Branched length 5}}<br>Arg, Leu, Ile<br>[[Image:BMAAB5.png|90px]]
+  |style="text-align:center"|Branched length 5<br>[[{{GetMetaboliteID|L-Arginine||BMAA}}|Arg]], [[{{GetMetaboliteID|L-Leucine||BMAA}}|Leu]], [[{{GetMetaboliteID|L-Isoleucine||BMAA}}|Ile]]<br>[[Image:BMAAB5.png|90px]]
   |{{MapLink|FunctionalGroupBM|BMAAB6}}
   |style="text-align:center"|Branched length 6<br>[[Image:BMAAB6.png|90px]]
   |-
-  ! colspan="6" |[[:Category:BMAC|Cyclic Class]]
+  ! colspan="6" |[[:Category:BMAC|Cyclic Class (click here to visit another page)]]
 |}
@@ Line 46: / Line 46: @@
 ! colspan = 7 | Character of amino acids
 |-
-| Name || Code || Symbol || Structure || Character || pI || Required for human?
+| ID || Code || Symbol || Structure || Character || pI || Required for human?
 |-
-| [[BMAAS3AK0003|alanine]] || Ala || A || -CH<sub>3</sub> || neutral || 6.0 ||
+| [[{{GetMetaboliteID|L-Alanine||BMAA}}]] || Ala || A || -CH<sub>3</sub> || neutral || 6.0 ||
 |-
-| serine || Ser || S || -CH<sub>2</sub>OH || neutral || 5.7 ||
+| [[{{GetMetaboliteID|L-Serine||BMAA}}]] || Ser || S || -CH<sub>2</sub>OH || neutral || 5.7 ||
 |-
-| threonine || Thr || T || -CH(OH)CH<sub>3</sub> || neutral || 5.6 || yes
+| [[{{GetMetaboliteID|L-Threonine||BMAA}}]] || Thr || T || -CH(OH)CH<sub>3</sub> || neutral || 5.6 || yes
 |-
-| valine || Val || V || -CH(CH<sub>3</sub>)<sub>2</sub> || neutral, branched || 6.0 || yes
+| [[{{GetMetaboliteID|L-Valine||BMAA}}]] || Val || V || -CH(CH<sub>3</sub>)<sub>2</sub> || neutral, branched || 6.0 || yes
 |-
-| leucine || Leu || L || -CH<sub>2</sub>CH(CH<sub>3</sub>)<sub>2</sub> || neutral, branched || 6.0 || yes
+| [[{{GetMetaboliteID|L-Leucine||BMAA}}]] || Leu || L || -CH<sub>2</sub>CH(CH<sub>3</sub>)<sub>2</sub> || neutral, branched || 6.0 || yes
 |-
-| isoleucine || Ile || I || -CH(CH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub> || neutral, branched || 6.0 || yes
+| [[{{GetMetaboliteID|L-Isoleucine||BMAA}}]] || Ile || I || -CH(CH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub> || neutral, branched || 6.0 || yes
 |-
-| aspartic acid || Asp || D || -CH<sub>2</sub>COOH || acidic || 2.8 ||
+| [[{{GetMetaboliteID|L-Aspartate||BMAA}}]] || Asp || D || -CH<sub>2</sub>COOH || acidic || 2.8 ||
 |-
-| glutamic acid || Glu || E || -CH<sub>2</sub>CH<sub>2</sub>COOH || acidic || 3.2 ||
+| [[{{GetMetaboliteID|L-Glutamate||BMAA}}]] || Glu || E || -CH<sub>2</sub>CH<sub>2</sub>COOH || acidic || 3.2 ||
 |-
-| asparagine || Asn || N || -CH<sub>2</sub>CONH<sub>2</sub> || acidic, amido || 5.4 ||
+| [[{{GetMetaboliteID|L-Asparagine||BMAA}}]] || Asn || N || -CH<sub>2</sub>CONH<sub>2</sub> || acidic, amido || 5.4 ||
 |-
-| glutamine || Gln || Q || -CH<sub>2</sub>CH<sub>2</sub>CONH<sub>2</sub> || acidic, amido || 5.7 ||
+| [[{{GetMetaboliteID|L-Glutamine||BMAA}}]] || Gln || Q || -CH<sub>2</sub>CH<sub>2</sub>CONH<sub>2</sub> || acidic, amido || 5.7 ||
 |-
-| lysine || Lys || K || -(CH<sub>2</sub>)<sub>4</sub>NH<sub>3</sub> || basic || 9.7 || yes
+| [[{{GetMetaboliteID|L-Lysine||BMAA}}]] || Lys || K || -(CH<sub>2</sub>)<sub>4</sub>NH<sub>3</sub> || basic || 9.7 || yes
 |-
-| arginine || Arg || R || -(CH<sub>2</sub>)<sub>3</sub>NHC(=NH)NH<sub>2</sub> || basic || 10.8 ||
+| [[{{GetMetaboliteID|L-Arginine||BMAA}}]] || Arg || R || -(CH<sub>2</sub>)<sub>3</sub>NHC(=NH)NH<sub>2</sub> || basic || 10.8 ||
 |-
-| cysteine || Cys || C || -CH<sub>2</sub>SH || neutral, S || 5.1 ||
+| [[{{GetMetaboliteID|L-Cysteine||BMAA}}]] || Cys || C || -CH<sub>2</sub>SH || neutral, S || 5.1 ||
 |-
-| methionine || Met || M || -(CH<sub>2</sub>)<sub>2</sub>SCH<sub>3</sub> || neutral, S || 5.7 || yes
+| [[{{GetMetaboliteID|L-Methionine||BMAA}}]] || Met || M || -(CH<sub>2</sub>)<sub>2</sub>SCH<sub>3</sub> || neutral, S || 5.7 || yes
 |-
-| phenylalanine || Phe || F || -CH<sub>2</sub>-Benz || neutral, aromatic || 5.5 || yes
+| [[{{GetMetaboliteID|L-Phenylalanine||BMAA}}]] || Phe || F || -CH<sub>2</sub>-Benz || neutral, aromatic || 5.5 || yes
 |-
-| tyrosine || Tyr || Y || -CH<sub>2</sub>-Benz-OH || neutral, aromatic || 5.7 ||
+| [[{{GetMetaboliteID|L-Tyrosine||BMAA}}]] || Tyr || Y || -CH<sub>2</sub>-Benz-OH || neutral, aromatic || 5.7 ||
 |-
-| tryptophan || Trp || W || -CH<sub>2</sub>-Indole || neutral, aromatic || 5.9 || yes
+| [[{{GetMetaboliteID|L-Tryptophan||BMAA}}]] || Trp || W || -CH<sub>2</sub>-Indole || neutral, aromatic || 5.9 || yes
 |-
-| histidine || His || H || -CH<sub>2</sub>-Imidazole || basic, atomatic || 7.6 || yes
+| [[{{GetMetaboliteID|L-Histidine||BMAA}}]] || His || H || -CH<sub>2</sub>-Imidazole || basic, atomatic || 7.6 || yes
 |-
-| proline || Pro || P || -NH-(CH<sub>2</sub>)<sub>3</sub>- || neutral, cyclic, 2nd amine || 6.2 ||
+| [[{{GetMetaboliteID|L-Proline||BMAA}}]] || Pro || P || -NH-(CH<sub>2</sub>)<sub>3</sub>- || neutral, cyclic, 2nd amine || 6.2 ||
 |}

@@ Line 18: / Line 18: @@
   |{{MapLink|FunctionalGroupBM|BMAAS2}}
   |style="text-align:center"|Straight length 2<br>Gly<br>[[Image:BMAAS2.png|90px]]
-  |{{LinkFunctionalGroupBM|BMAAS3}}
+  |{{MapLink|FunctionalGroupBM|BMAAS3}}
   |style="text-align:center"|Straight length 3<br>Ser, Cys, [[BMAAS3AK0003|Ala]]<br>[[Image:BMAAS3.png|90px]]
-  |{{LinkFunctionalGroupBM|BMAAS4}}
+  |{{MapLink|FunctionalGroupBM|BMAAS4}}
   |style="text-align:center"|{{SearchLink/Main|Straight length 4}}<br>Asp, Asn, Thr<br>[[Image:BMAAS4.png|90px]]
   |-
-  |{{LinkFunctionalGroupBM|BMAAS5}}
+  |{{MapLink|FunctionalGroupBM|BMAAS5}}
   |style="text-align:center"|Straight length 5<br>Gln, Glu<br>[[Image:BMAAS5.png|90px]]
-  |{{LinkFunctionalGroupBM|BMAAS6}}
+  |{{MapLink|FunctionalGroupBM|BMAAS6}}
   |style="text-align:center"|Straight length 6<br>Lys<br>[[Image:BMAAS6.png|90px]]
   | ||
@@ Line 31: / Line 31: @@
   ! colspan="6"| Branched Class
   |-
-  |{{LinkFunctionalGroupBM|BMAAB4}}
+  |{{MapLink|FunctionalGroupBM|BMAAB4}}
   |style="text-align:center"|Branched length 4<br>Val, Met<br>[[Image:BMAAB4.png|90px]]
-  |{{LinkFunctionalGroupBM|BMAAB5}}
+  |{{MapLink|FunctionalGroupBM|BMAAB5}}
   |style="text-align:center"|{{SearchLink/Main|Branched length 5}}<br>Arg, Leu, Ile<br>[[Image:BMAAB5.png|90px]]
-  |{{LinkFunctionalGroupBM|BMAAB6}}
+  |{{MapLink|FunctionalGroupBM|BMAAB6}}
   |style="text-align:center"|Branched length 6<br>[[Image:BMAAB6.png|90px]]
   |-

@@ Line 16: / Line 16: @@
   ! colspan="6"| Straight Class
   |-
-  |{{SearchLink/Main|BMAAS2|BMAAS2}}
+  |[[Volatile:FunctionalGroupBM|BMAAS2|BMAAS2]]
   |style="text-align:center"|Straight length 2<br>Gly<br>[[Image:BMAAS2.png|90px]]
   |{{SearchLink/Main|BMAAS3|BMAAS3}}